@charset "UTF-8";
body {
  font-family: 'IBM Plex Sans', sans-serif, 'Noto Sans JP';
}

#fh5co-loader {
  position: fixed;
  left: 0px;
  top: 0px;
  width: 100%;
  height: 100%;
  z-index: 999999;
  background: url(../../images/pcf/loader.gif) center no-repeat #fff;
}

.search-header {
  z-index: 99;
  position: sticky;
  /*top: 0;*/
  top: 24px; /*skip the common-header*/
  background-size: cover;
  background-color: #f0f0f0;
  overflow: hidden;
}

.search-header .search-header_wrapper {
  justify-content: space-between;
  align-items: flex-start;
  flex-wrap: wrap;
  padding-top: 0.75rem;
  /*padding-bottom: 1rem;*/
  border-bottom: solid 1px #ddd;
}

.search-header .search-header_wrapper .search-header_top {
  display: flex;
  width: 100%;
  height: 50px;
  min-width: 700px;
}

.search-header .search-header_wrapper .search-header_top .brand {
  display: block;
  /*width: 37%;*/
  width:  200px;
  margin-left: 15px;
}

.search-header .search-header_wrapper .search-header_top .search-header_left {
  margin: 0 0 0 auto;
  display: flex;
  justify-content: center;
  align-items: center;
}

.search-header .search-header_wrapper .search-header_top .search-header_left .language {
    margin-right: 1.5em;
	margin-left:  1em;
    white-space: nowrap;
    transition: all 0.5s 0s ease;
    text-align: none;
    line-height: 1.42857;
    position: relative;
    border-radius: 2em;
    background-color: #fafafa;
    padding: 10px 10px 10px 40px;
    max-width: 110px;
}

  .select-text {
    position: relative;
    font-family: inherit;
    background-color: transparent;
    border-radius: 0;
    border: none;
    border-radius: 2em;
    width: 100%;
  }

  .select-text:focus {
    outline: none;
    border-bottom: 1px solid rgba(0,0,0, 0);
  }

  .select .select-text {
    appearance: none;
    -webkit-appearance:none
  }

  .select:after {
    position: absolute;
    top: 18px;
    right: 10px;
    /* Styling the down arrow */
    width: 0;
    height: 0;
    padding: 0;
    content: '';
    border-left: 6px solid transparent;
    border-right: 6px solid transparent;
    border-top: 6px solid rgba(0, 0, 0, 0.12);
    pointer-events: none;
  }

  .select-label {
    color: rgba(0,0,0, 0.26);
    font-weight: normal;
    position: absolute;
    pointer-events: none;
    left: 0;
    top: 10px;
    transition: 0.2s ease all;
  }

  .select-text:focus ~ .select-label, .select-text:valid ~ .select-label {
    color: #2F80ED;
    transition: 0.2s ease all;
    padding-left: 12px;
  }
  .select-bar {
    position: relative;
    display: block;
    width: 100px;
  }


  .select-bar:before, .select-bar:after {
    content: '';
    height: 2px;
    width: 0;
    bottom: 1px;
    position: absolute;
    background: #2F80ED;
    transition: 0.2s ease all;
  }
/*
@media (max-width: 970px){
    .search-header .search-header_wrapper .search-header_top .search-header_left .language {
        margin-left: 1em;
        margin-right: 0;
    }
}
*/
.search-header .search-header_wrapper .search-header_top .search-header_left span a{
  text-decoration: none;
}

.search-header .search-header_wrapper .search-header_top .search-header_left .site-header_end {
  border: solid 1px #888888;
  border-radius: 5px;
  margin-right: 20px;
  background-color: #fff;
}

.search-header .search-header_wrapper .search-header_top .search-header_left .site-header_end a {
  color: #394466;
  display: flex;
  justify-content: center;
  align-items: center;
  padding: 5px 0px 5px 7px;
  font-weight: 500;
}

.search-header .search-header_wrapper .search-header_top .search-header_left .site-header_end a i {
  color: #394466;
  margin-left: 0.5rem;
  border-left: solid 1px #AEB0B5;
}

.search-header .search-header_wrapper .search-box_wrapper {
  width: 64%;
  min-width: 680px;
  margin: -55px auto 0 auto;
}

#text2hpo a:hover, #text2hpo a:visited, #text2hpo a:link, #text2hpo a:active
{
    text-decoration: none;
}


.search-header .search-header_wrapper .search-box_wrapper .search-button {
  display: flex;
  flex-wrap: wrap;
  padding-top: 0.5rem;
  padding-bottom: 10px;
  font-weight: 400;
  min-width:  700px;
  width: 100%;
}

.search-header .search-header_wrapper .search-box_wrapper .search-button button {
  border: solid 1px #AEB0B5;
  border-radius: 5px;
  color: black;
  padding: 5px;
  display: flex;
  justify-content: center;
  align-items: center;
  margin-right: 0.5em;
}

.search-header .search-header_wrapper .search-box_wrapper .search-button button[disabled]{
  color: gray;
}

.search-header .search-header_wrapper .search-box_wrapper .search-button button[aria-expanded="true"] {
  border: solid 1px #394466;
  background-color: #394466;
  color: #fff;
}

.search-header .search-header_wrapper .search-box_wrapper .search-button button[aria-expanded="true"] i {
  transform: rotateX(180deg);
  transition: all 0.5s;
}

#btn_search_filter,#btn_search_vgp {
  padding-left: 0.7em;
}

#btn_search_display {
  margin-right: 0;
  left: 0;
  margin-left: auto;
  padding-left: 0.7em;
}

.action-button {
  padding: 0.5em;
  border-radius: 5px;
  justify-content: center;
  border: solid 1px #394466;
  background-color: #394466;
  color: #fff;
  margin-right: 0.5rem;
}

.action-button:disabled {
  color: #fff;
  background-color: #6c757d;
  border-color: #6c757d;
}

.cancel-button {
  padding: 0.5em;
  border-radius: 5px;
  justify-content: center;
  border: solid 1px #394466;
}

.search-header .search-header_wrapper .search-advanced {
  background-color: white;
  width: 100%;
  border-bottom: 1px solid #DDD;
}

.search-header .search-header_wrapper .search-advanced .search-box-advanced_wrapper {
  width: 65%;
  min-width: 700px;
  /*padding-top:2.0rem;*/
  padding-top:0.8rem;
  /*padding-bottom:2.0rem;*/
  padding-bottom:1rem;
  margin: 0 auto 0 auto;
}

.search-header .search-header_wrapper .search-advanced .search-box-advanced_wrapper .search-box-filter_title{
	display: flex;
    flex-wrap: wrap;
    padding-top: 0.5rem;
    padding-bottom: 5px;
    font-weight: 400;
    min-width: 700px;
    width: 100%;
}

.search-header .search-header_wrapper .search-advanced .search-box-advanced_wrapper .search-box-filter_title b,font {
	display: inline-block;
	margin-top:10px;
}

.search-header .search-header_wrapper .search-advanced .search-box-advanced_wrapper .search-box-filter_title a {
    display: inline-block;
    margin-top:10px;
	margin-bottom:3px;
}



.search-header .search-header_wrapper .search-advanced .search-box-advanced_wrapper .search-box-filter_title i{
border-radius: 50%;
    background-color: #AEB0B5;
    color: #fff;
    font-size: 13px;
    margin: 13px 0px 2px 5px;
    padding-left: 2px;
    padding-top: 2px;
    width: 18px;
    height: 18px;
    display: inline-block;
}

.in-circle {
    display: inline-block;
    background: #AEB0B5;
    color: #fff;
    border-radius: 50%;
    width: 14px;
    height: 14px;
    line-height: 14px;
    text-align: center;
    font-size: 10px;
    margin-top: 15px;
    margin-left: 5px;
    font-family: Verdana;
}


#btn_vgp_textinput {
    border: solid 1px #AEB0B5;
    border-radius: 5px;
    color: black;
    padding: 5px;
    display: flex;
    justify-content: center;
    align-items: center;
    margin-left:  10px;
}

#btn_vgp_download {
    border: solid 1px #AEB0B5;
    border-radius: 5px;
    color: black;
    padding: 5px;
    display: flex;
    justify-content: center;
    align-items: center;
    margin-left:  auto;
}

#btn_filter_textinput {
    border: solid 1px #AEB0B5;
    border-radius: 5px;
    color: black;
    padding: 5px;
    display: flex;
    justify-content: center;
    align-items: center;
    margin-left:  auto;
}


#btn_vgp_expand {
  background-color: #485d9d;
  border-radius: 15px;
  margin-top: 5px;
  color: #fff;
  padding-left: 10px;
  padding-bottom: 2px;
}

#btn_vgp_expand i {
  vertical-align: bottom;
  margin-right: 3px;
}

.change-color {
  background-color: #fff;
  box-shadow: 0 0 10px rgba(0, 0, 0, 0.3);
  transition: 0.5s;
}

.content-wrapper {
  margin: 0 auto;
  width: 64%;
  min-width: 680px;
}

.content-wrapper .content-panel {
  /*margin:   10px auto;*/
  margin:   10px 0;
  position: relative;
  min-height: 100px;
}

.content-wrapper .content-panel .tab-button-panel {
  width:100%;
}

.content-wrapper .content-panel .tab-button-panel span {
  padding-bottom: 10px;
  color: #394466;
  cursor: pointer;
  border-bottom: 1px solid #ddd;
  display: flex;
  width: 25%;
  float: left;
  height: 40px;
  line-height: 40px;
  font-weight: 500;
  align-items: center;
}

.content-wrapper .content-panel .tab-button-panel span i {
  margin-right: 0.2em;
}

.content-wrapper .content-panel .tab-button-panel span.pcf-active {
  border-bottom: 5px solid #394466;
}

.tab-button-omim {
  left: 0;
}

.tab-button-orphanet {
  left: 25%;
}

.tab-button-gene {
  left: 50%;
}

.tab-button-case {
  left: 75%;
}


.tab-content-wrapper {
  padding-top: 0.3em;
  display: block;
  color: #000;
  width: 100%;
}

.tab-content-wrapper .tab-content-panel {
  display: none;
  width: 100%;
}

.tab-content-wrapper .tab-content-panel.pcf-active {
  display: block;
}

.tab-content-wrapper .tab-content-panel:empty:before{
  content: attr(placeholder);
}


/*症状一覧*/
.list-header {
  border-bottom: 1px solid #ddd;
  width: 100%;
/*  margin-top: 30px;*/
  padding: 1em 0;
}
.list-header .list-header-up{
  width: 100%;
  display: flex;
  flex-wrap: wrap;
  gap: 10px 5px;
}

.list-header .list-header-up div{
    align-content: center;
}
.list-header .list-header-up .list-results {
  color: #555555;
}

.list-header .list-header-up .list-results-select-num {
  margin-left: 15px;
}

.list-header .list-header-up .list-results-clear-select {
  margin-left: 15px;
  color: #555555;
  cursor: pointer;
}

.list-header .list-header-up .list-tag_sample {
  margin: 0 0 0 auto;
}

.list-header .list-header-up .list-tag_sample span {
  border-radius: 5px;
  margin-left: 5px;
  padding: 3px;
}

.list-header .list-header-up .list-tag_sample span.list-tag_blue {
  color: #067ABC;
  border: 1.5px solid #067ABC;
}

.list-header .list-header-up .list-tag_sample span.list-tag_green {
  color: #2F9145;
  border: 1.5px solid #2F9145;
}

.list-header .list-header-up .list-tag_sample span.list-tag_gray {
  color: #777777;
  border: 1.5px solid #777777;
}

.list-header .list-header-up .list-tag_sample span.list-tag_red {
  color: #d9534f;
  border: 1.5px solid #d9534f;
}

.list-header .list-header-down{
  width: 100%;
  margin-top: 10px;
  background-color: #DFF4FF;
  font-color: #3790C2;
  border: 1px solid #3790C2;
  border-radius: 5px;
  display: none;
  padding: 0.5em 0;
  color: #3790C2;
}
.list-header .list-header-down.active{
  display:flex;
  flex-direction: row;
}
.list-header .list-header-down .material-symbols-outlined{
  background-color: #3790C2;
  color: white;
  border-radius: 50%;
  font-size: 15px;
  height: 15px;
  width: 15px;
  margin-top: 3px;
}
.list-header .list-header-down .clickable{
  cursor:pointer;
  text-decoration: underline;
  text-underline-offset: 4px;
  white-space: nowrap;
}

.list-content {
  display: flex;
  margin: 15px 0 0 0;
  padding-bottom: 1em;
  border-bottom: 1px solid #ddd;
}

.list-content-pagenum {
  display: flex;
  margin: 15px 0 0 0;
  padding-bottom: 15px;
  border-bottom: 1px solid #ddd;
}


.list-content-pagenum .list-content_center {
  width:         100%;
  /*height:        40px;*/
  text-align:    center;
}

.list-content .list-content_left.full,
.list-content .list-content_left.summary {
  margin-right: 2em;
  width:         60px;
  min-width:     60px;
  text-align:    right;
  line-height:   1.15;
}

.list-content .list-content_left.full .rank,
.list-content .list-content_left.summary .rank{
  text-align: center;
  display: inline-block;
}

.rank input[type="checkbox"] {
  -webkit-appearance: none; /*ChromeやSafari用*/
  -moz-appearance: none; /*Firefox用*/
  appearance: none;
  position: relative;
  width: 1.5em;
  height: 1.5em;
  color: black;
  border: 1px solid gray;
  border-radius: 4px;
  appearance: none;
  outline: 0;
  cursor: pointer;
  transition: background 175ms cubic-bezier(0.1, 0.1, 0.25, 1);
  margin-bottom: 0.5em;
}

.rank input[type="checkbox"]::before {
  position: absolute;
  content: '';
  display: block;
  top: 2px;
  left: 7px;
  width: 8px;
  height: 14px;
  border-style: solid;
  border-color: white;
  border-width: 0 2px 2px 0;
  transform: rotate(45deg);
  opacity: 0;
}

.rank input[type="checkbox"]:checked {
  color: white;
  border-color: #394466;
  background: #394466;
}

.rank input[type="checkbox"]:checked::before {
  opacity: 1;
}

.rank input[type="checkbox"]:checked ~ label::before {
  clip-path: polygon(0 0, 100% 0, 100% 100%, 0 100%);
}

.rank label {
  position: relative;
  cursor: pointer;
  font-size: 1.5em;
  font-weight: 600;
  padding: 0 0.25em 0;
  user-select: none;
}


.list-content .list-content_left.full span,
.list-content .list-content_left.summary span{
  display: block;
  margin-bottom: 1em;
  color: #707070;
}

.list-content .list-content_left span.summary {
  margin-bottom: 0.3em;
}

.list-content .list-content_left .list-content_left_bt {
  float: right;
}

.list-content .list-content_left .list-content_left_bt a {
  color: #707070;
  display: flex;
  justify-content: flex-end;
  cursor: pointer;
  text-decoration: none;
}

.list-content .list-content_left .list-content_left_bt.summary a {
  display: inline-block;
}

.list-content .list-content_left .list-content_left_bt a:hover {
  color: #0431B4;
}

.list-content .list-content_left .list-content_left_bt a[aria-expanded="true"] {
  color: #0431B4;
}

.list-content .list-content_left .list-content_left_bt a.liked {
  color: #0431B4;
}


.list-content .list-content_left .list-content_left_bt a i {
  font-size: 1.2em;
  margin-bottom: 1em;
  margin-left: 0.1em;
}

.list-content .list-content_left .list-content_left_bt.summary a i {
  margin-bottom: 0.3em;
}




.list-content .list-content_left.short {
  width:        180px;
  min-width:    180px;
  max-width:    180px;
  line-height:  1.0;
  padding-top:  3px; 
}

.list-content .list-content_left.short div {
  color: #707070;
  margin-right: 5px;
  height: 24px;
}

.list-content .list-content_left.short .sel {
  text-align: center;
}

.list-content .list-content_left.short .sel input[type="checkbox"] {
  -webkit-appearance: none; /*ChromeやSafari用*/
  -moz-appearance: none; /*Firefox用*/
  appearance: none;
  position: relative;
  width: 1.3em;
  height: 1.3em;
  color: black;
  border: 1px solid gray;
  border-radius: 4px;
  appearance: none;
  outline: 0;
  cursor: pointer;
  transition: background 175ms cubic-bezier(0.1, 0.1, 0.25, 1);
  /*margin-bottom: 0.5em;*/
}

.list-content .list-content_left.short .sel input[type="checkbox"]::before {
  position: absolute;
  content: '';
  display: block;
  top: 2px;
  left: 7px;
  width: 8px;
  height: 14px;
  border-style: solid;
  border-color: white;
  border-width: 0 2px 2px 0;
  transform: rotate(45deg);
  opacity: 0;
}

.list-content .list-content_left.short .sel input[type="checkbox"]:checked {
  color: white;
  border-color: #394466;
  background: #394466;
}

.list-content .list-content_left.short .sel input[type="checkbox"]:checked::before {
  opacity: 1;
}

.list-content .list-content_left.short .sel input[type="checkbox"]:checked ~ label::before {
  clip-path: polygon(0 0, 100% 0, 100% 100%, 0 100%);
}



.list-content .list-content_left.short .rank {
  color: #000;
}

.list-content .list-content_left.short div a {
  color: #707070;
  cursor: pointer;
  text-decoration: none;
}

.list-content .list-content_left.short div a:hover {
  color: #0431B4;
}

.list-content .list-content_left.short div a[aria-expanded="true"] {
  color: #0431B4;
}

.list-content .list-content_left.short div a.liked {
  color: #0431B4;
}


.list-content .list-content_left.short div a i {
  font-size: 1.2em;
}

.list-content .list-content_right {
  line-height: 1.15;
}

.list-content .list-content_right .title {
  width: 100%;
/*  margin-bottom: 0.3em;*/
}
.list-content .list-content_right .title .ctl {
  cursor: pointer;
}
.list-content .list-content_right .title .ctl.full {
  transform: rotateX(180deg);
}

.list-content .list-content_right .title h3 {
  font-size: 1.3em;
 /* margin-bottom: 0.1em;*/
}

.list-content .list-content_right.short .title h3 {margin-bottom: 0;}

.list-content .list-content_right h2 {
  font-size: 1.1em;
  margin-bottom: 0.5em;
}

.list-content .list-content_right.short h2 {
  margin-bottom: 0;
}

.list-content .list-content_right .list-tag-wrapper {
  display: -ms-flexbox;
  display: flex;
  flex-wrap: wrap;
  -ms-flex-wrap: wrap;
}

.list-content .list-content_right.short   .list-tag-wrapper {display: none;}

.list-content .list-content_right .list-tag-wrapper .list-tag {
  border-radius: 5px;
  padding: 3px;
  margin-right: 0.3em;
  margin-bottom: 0.3em;
  cursor: pointer;
  -webkit-transition: background 0.2s,color 0.1s;
  transition: background 0.2s,color 0.1s;
  border: 1.5px solid black;
}

.list-content .list-content_right .list-tag-wrapper .list-tag.list-tag_blue{
  border-color: #067ABC;
}
.list-content .list-content_right .list-tag-wrapper .list-tag.list-tag_blue[aria-expanded="false"] {
  color: #067ABC;
}

.list-content .list-content_right .list-tag-wrapper .list-tag.list-tag_blue:hover {
  color: #fff;
  background-color: #067ABC;
  transition: 0.5s;
}

.list-content .list-content_right .list-tag-wrapper .list-tag.list-tag_blue[aria-expanded="true"] {
  color: #fff;
  background-color: #067ABC;
  transition: 0.5s;
}


.list-content .list-content_right .list-tag-wrapper .list-tag.list-tag_green {
  border-color: #2F9145;
}

.list-content .list-content_right .list-tag-wrapper .list-tag.list-tag_green[aria-expanded="false"] {
  color: #2F9145;
}

.list-content .list-content_right .list-tag-wrapper .list-tag.list-tag_green:hover {
  color: #fff;
  background-color: #2F9145;
  transition: 0.5s;
}

.list-content .list-content_right .list-tag-wrapper .list-tag.list-tag_green[aria-expanded="true"] {
  color: #fff;
  background-color: #2F9145;
  transition: 0.5s;
}

.list-content .list-content_right .list-tag-wrapper .list-tag.list-tag_gray {
  border-color: #777777;
}

.list-content .list-content_right .list-tag-wrapper .list-tag.list-tag_gray[aria-expanded="false"] {
  color: #777777;
}

.list-content .list-content_right .list-tag-wrapper .list-tag.list-tag_gray:hover {
  color: #fff;
  background-color: #777777;
  transition: 0.5s;
}

.list-content .list-content_right .list-tag-wrapper .list-tag.list-tag_gray[aria-expanded="true"] {
  color: #fff;
  background-color: #777777;
  transition: 0.5s;
}

.list-content .list-content_right .list-tag-wrapper .list-tag.list-tag_red {
  border-color: #d9534f;
}

.list-content .list-content_right .list-tag-wrapper .list-tag.list-tag_red[aria-expanded="false"] {
  color: #d9534f;
}

.list-content .list-content_right .list-tag-wrapper .list-tag.list-tag_red:hover {
  color: #fff;
  background-color: #d9534f;
  transition: 0.5s;
}

.list-content .list-content_right .list-tag-wrapper .list-tag.list-tag_red[aria-expanded="true"] {
  color: #fff;
  background-color: #d9534f;
  transition: 0.5s;
}


.list-content .list-content_right p {
  padding: 0.2em 0;
  line-height: 1.5em;
}

.list-content .list-content_right.summary p {display: none;}
.list-content .list-content_right.short   p {display: none;}

.list-content .list-content_right p a {color: #0431B4;}

.list-content .list-content_right .list-link {
  margin-top: 0.4em;
  margin-bottom: 0.6em;
  line-height:  1.15;
  display: flex;
  flex-wrap: wrap;
  -ms-flex-wrap: wrap;
}


.list-content .list-content_right.summary .list-link {display: none;}
.list-content .list-content_right.short   .list-link {display: none;}

.list-content .list-content_right .list-link a {
  color: #0431B4;
  margin-right: 0.7em;
  margin-bottom: 0.3em;
  text-decoration: underline;
  cursor: pointer;
  text-underline-offset: 4px;
}
}

.list-content .list-content_right .list-show_wrapper {width: 100%;}

.list-content .list-content_right.summary .list-show_wrapper {display: none;}
.list-content .list-content_right.short   .list-show_wrapper {display: none;}

.list-content .list-content_right .list-show_wrapper .list-show {display: flex;}

.list-content .list-content_right .list-show_wrapper .list-show a {
  display: inline-flex;
  margin-right: 0.7em;
  cursor: pointer;
  line-height: 1.15;
}
.list-content .list-content_right .list-show_wrapper .list-show  a:hover {
  color: inherit;
  text-decoration: none;
}

.list-content .list-content_right .list-show_wrapper .list-show a span {
  display: flex;
  color: #394466;
}
.list-content .list-content_right .list-show_wrapper .list-show a span:before {
  font-feature-settings: 'liga';
  font-family: 'Material Icons';
  content: '\e146';
  font-weight: normal;
  font-style: normal;
  font-size: 1.2em;
  line-height: 1;
  letter-spacing: normal;
  text-transform: none;
  display: inline-block;
  vertical-align: text-bottom;
  white-space: nowrap;
  word-wrap: normal;
  direction: ltr;
  -webkit-font-feature-settings: 'liga';
  -webkit-font-smoothing: antialiased;
  color: #394466;
}

.list-content .list-content_right .list-show_wrapper .list-show a.pcf-active span {color: red;}

.list-content .list-content_right .list-show_wrapper .list-show a.pcf-active span:before {
  content: '\e909';
  color: red;
}

.list-content .list-content_right .list-show_wrapper .list-show-panel {
  margin-top: 15px;
  display: none;
  width:   100%;
  min-height: 40px;
  padding-left: 15px;
  padding-right: 15px;
}
/*
.list-content .list-content_right .list-show_wrapper .list-show-panel.status-empty {
  background-color: #fff;
  background: url(../../images/pcf/loader-32px.gif) center no-repeat #fff; 
}
*/
.status-empty {
  background-color: #fff;
  background: url(../../images/pcf/loader-32px.gif) center no-repeat #fff;
}

.list-content .list-content_right .list-show_wrapper .list-show-panel.pcf-active {
  display: block;
  border: 1px solid #ddd;
  font-weight: normal;
}

.list-content .list-content_right .list-show_wrapper .list-show-panel.pcf-active label {
  margin-top: 1.0rem;
  margin-bottom:0.2rem;
  color: #256D80;
  font-weight: 420;
}

.list-content .list-content_right .list-show_wrapper .list-show-panel.pcf-active table {
    width: 100%;
    text-align: left;
    border-collapse: collapse;
    margin: 0;
    border: 1px solid #EEEEEE;
    box-shadow: 1px 1px 3px 1px #EEEEEE;
}

.list-content .list-content_right .list-show_wrapper .list-show-panel.pcf-active table > thead > tr > th:first-child {
    padding-left: 20px;
    padding-right: 10px;
    width: 50px;
}

.list-content .list-content_right .list-show_wrapper .list-show-panel.pcf-active table > thead > tr > th {
    background-color: #256D80;
    color: #FFFFFF;
    font-size: 12px;
    font-weight: 400;
    padding: 10px;
    white-space: nowrap;
}


.list-content .list-content_right .list-show_wrapper .list-show-panel.pcf-active table tbody {
    display: table-row-group;
    vertical-align: middle;
    border-color: inherit;
    font-size: 12px;
    background-color: #ffffff;
}

.list-content .list-content_right .list-show_wrapper .list-show-panel.pcf-active table > tbody > tr:nth-child(odd) {
    background-color: rgba(255,255,255,0);
}

.list-content .list-content_right .list-show_wrapper .list-show-panel.pcf-active table > tbody > tr:last-of-type > td {
    border-bottom: none;
}

.list-content .list-content_right .list-show_wrapper .list-show-panel.pcf-active table > tbody > tr > td:first-child {
    padding-left: 40px;
    width: 50px;
}

.list-content .list-content_right .list-show_wrapper .list-show-panel.pcf-active table > tbody > tr > td {
    border-bottom: 1px solid #EEEEEE;
    border-collapse: collapse;
    padding: 10px;
}

.list-content .list-content_right .list-show_wrapper .list-show-panel.pcf-active table > tbody > tr > td > span {
  cursor: pointer;
  color:  #256D80;
  font-size: 22px;
  vertical-align: text-top;
}

.list-content .list-content_right .list-show_wrapper .list-show-panel.pcf-active table > tbody > tr > td > button {
  border-radius: 5px;
  padding: 3px;
  color:   #256D80;
  border:  1.5px solid #256D80;
  white-space: nowrap;
  font-size: 1rem;
}

.list-content .list-content_right .list-show_wrapper .list-show-panel.pcf-active table > tbody > tr > td > button:hover {
  color:   #fff;
  background-color: #256D80;
}

.list-content .list-content_right .list-show_wrapper .list-show-panel.pcf-active table > tbody > tr > td > button[aria-expanded="true"] {
  color:   #fff;
  background-color: #256D80;
}


.list-content .list-content_right .list-show_wrapper .list-show-panel.pcf-active table > tbody > tr > td > a {
  color: #256D80;
  text-decoration: none;
  cursor: pointer;
}

.list-footer {
  border-bottom: 1px solid #ddd;
  width: 100%;
  display: flex;
  padding: 1em 0;
}

.list-footer .list-results {
  color: #555555;
  margin: auto 0;
}

.list-footer button {
  display: inline-flex;
  margin: 0 auto;
}

.list-footer button span {
  width: 2.5em;
  height: 2.5em;
  border-radius: 20px;
  /*background-color: #f73859;*/
  background-color: #f8516d;
  padding-top: 7px;
}

.list-footer button span i {
  font-size: 1.5em;
  font-weight: 600;
  color: #fff;
}

.list-footer button p {
  font-weight: 500;
  margin: auto 0;
  padding-left: 0.3em;
}

.list-footer a {
  text-decoration: underline;
  margin: 0 0 0 auto;
  margin: auto 0;
  color: #555555;
}

/*Checkboxes styles終了*/
.footer_img {
  width: 100%;
  margin-top: 20px;
}

.v_line_left {
  border-left: 1px solid #d6d6d6;
  padding-left: 0.7em;
}

/*fontello*/
.icon-omim:before {
  content: '\e80a';
  font-size: 1.2em;
}

.icon-orphanet:before {
  content: '\e80b';
  font-size: 1.2em;
}

.icon-gene:before {
  content: '\e80d';
  font-size: 1.5em;
}

.icon-case:before {
  content: '👥';
  font-size: 1.2em;
}

#ul_menu {
  width: 90px;
  background: #394466;
}

#ul_menu a {
  color: #fff;
  padding: 10px 15px;
  display: block;
  text-decoration: none;
}

#ul_menu a:hover {
  color: #fff;
  text-decoration: none;
}

/* ホバーで子メニュー表示 */
#ul_menu li a:hover {
  background: #121a36;
}

.global-header {
  top: 24px;
}


.btn {
    display: inline-block;
    text-align:center;
    vertical-align: middle;
    touch-action: manipulation;
    cusor: pointer;
    white-space: nowrap;
    line-height: 1.42857;
    margin-right: 4px;
    margin-bottom: 4px;
    font-family: "Open Sans", Arial, sans-serif;
    font-size: 16px;
    font-weight: 400;
    -webkit-border-radius: 4px;
    -moz-border-radius: 4px;
    -ms-border-radius: 4px;
    border-radius: 4px;
    -webkit-transition: 0.5s;
    -o-transition: 0.5s;
    transition: 0.5s;
    padding: 8px 20px;
}

.btn-default {
    color: #333;
    background-color: #fff;
}

.btn-primary {
    background: #F73859;
    color: #fff;
    border: 2px solid #F73859;
}
.btn-primary:hover, .btn-primary:focus, .btn-primary:active {
    background: #f8516d !important;
    border-color: #f8516d !important;
}
.btn-primary.btn-outline {
    background: transparent;
    color: #F73859;
    border: 2px solid #F73859;
}
.btn-primary.btn-outline:hover, .btn-primary.btn-outline:focus, .btn-primary.btn-outline:active {
    background: #F73859;
    color: #fff;
}

#btn_back_to_top {
  display: none;
  position: fixed;
  bottom: 20px;
  right: 30px;
  z-index: 99;
  font-size: 18px;
  border: solid 1px #AEB0B5;
  cursor: pointer;
  border-radius: 4px;
  background-color: #394466;
  color: #fff;
}
#btn_back_to_top span {
  background-color: #394466;
  color: #fff;
  width: 100%;
  transform: rotateX(90deg);
}

.dropdown-menu {
  border:0;
  box-shadow: 0 0 8px gray;
}

.dropdown-menu-wrapper {
  display: none;
}

#dropdown-menu_download table tr {
  border:none;
}

#dropdown-menu_share table tr {
  border:none;
}

#dropdown-menu_display table tr {
  border:none;
}


.vertical-center {
  margin: 0;
  position: relative;
  top: 40%;
  -ms-transform: translateY(-50%);
  transform: translateY(-50%);
}


.popover {
  width: 320px;
  max-width: 450px;
  border: 0;
  box-shadow: 0 0 8px gray;
}

.popover .popover-body {
  padding: 0;
}

.title-case a{
  color: #0431B4;
}

.filter-sample {
  color: #13295A;
  background-color: #E2ECF4;
  padding: 3px 4px;
  margin-left: 3px;
  font-size:  0.8em;
  border-radius: 3px;
}

.filter-sample:hover {
  text-decoration: none;
  color: #13295A;
  background-color: #AECFE8; 
}