Malignant mixed Müllerian tumor of the ovary

Malignant mixed Müllerian tumor of the ovary is a rare and very aggressive neoplasm presenting most commonly in postmenopausal women and is composed of adenocarcinomatous and sarcomatous elements and, depending on the types of these elements, can be classified as homologous or heterologous. It often has a poor prognosis.



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Total: 28 (papers)

   


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Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)		 PMID
(PMCID)
2
(4.0%)		 11321500
 Malignant mixed mullerian tumor of the ovary: report of four cases.
Melilli GA, Nappi L, Carriero C, Lapresa M, Loizzi V, Caradonna F, Quaranta M, Putignano G.
Eur J Gynaecol Oncol. 2001;22(1):67-9.
Neoplasm
Combined Modality Therapy Females Homo sapiens Middle Aged Mixed Tumor, Mullerian
2
(4.0%)		 11285039
 Carcinosarcoma of ovary associated with previous radiotherapy.
Wei LH, Huang CY, Cheng SP, Chen CA, Hsieh CY.
Int J Gynecol Cancer. 2001;11(1):81-4.
Hepatic failure
Antineoplastic Combined Chemotherapy Protocols Carcinosarcoma Combined Modality Therapy Fatal Outcome Females Hepatitis B Homo sapiens Neoplasms, Radiation-Induced Uterine Cervical Neoplasm
2
(4.0%)		 10820916
 Malignant mixed mullerian tumors of the ovary.
Wei CF, Hwang SH, Ho CM, Shih BY, Chien TY.
Zhonghua Yi Xue Za Zhi (Taipei). 2000;63(4):344-8.
Carcinoma
DES S100A1 VIM
Adult Females Homo sapiens Middle Aged Mixed Tumor, Mullerian
2
(4.0%)		 10726444
 [Chemotherapy in the treatment of ovarian carcinosarcoma].
Melilli GA, Di Vagno G, Cormio G, Greco P, Fontana A, Carriero C, Loverro G, Selvaggi L.
Minerva Ginecol. 1999;51(11):445-8.
Renal insufficiency
Antineoplastic Agents, Alkylating Antineoplastic Agents, Phytogenic Antineoplastic Combined Chemotherapy Protocols Carcinosarcoma Females Homo sapiens Middle Aged Retrospective Studies
2
(4.0%)		 10637076
 Carcinosarcoma of the ovary in a patient with a germline BRCA2 mutation: evidence for monoclonal origin.
Sonoda Y, Saigo PE, Federici MG, Boyd J.
Gynecol Oncol. 2000;76(2):226-9.
Breast carcinoma
BRCA1 BRCA2 TP53
BRCA2 Protein Carcinosarcoma DNA Mutational Analysis Females Germ-Line Mutation Homo sapiens Neoplasm Proteins Tumor Suppressor Genes
2
(4.0%)		 8281496
 Malignant mixed mullerian tumor of the ovary: report of a case and review of the literature.
Shy SW, Lee WH, Lee MS, Lee MC.
Zhonghua Yi Xue Za Zhi (Taipei). 1993;51(6):468-73.
Carcinoma
Females Homo sapiens Immunohistochemistry Malignant Mixed Tumor Middle Aged Mixed Tumor, Mullerian
2
(4.0%)		 3457508
 Ascitic fluid cytology in a case of metastatic malignant mixed mesodermal tumor of the ovary.
Silverman JF, Gardner J, Larkin EW, Finley JL, Norris HT.
Acta Cytol. 1986;30(2):173-6.
Ovarian neoplasm
Ascitic Fluid Epithelium Females Homo sapiens Hysterectomy Omentum Ovariectomy Ovary
2
(4.0%)		 2197242
 Malignant mixed mullerian tumor of the ovary with prominent neuroectodermal differentiation (teratoid carcinosarcoma).
Ehrmann RL, Weidner N, Welch WR, Gleiberman I.
Int J Gynecol Pathol. 1990;9(3):272-82.
Teratoma
Carcinosarcoma Females Histocytochemistry Homo sapiens Immunoenzyme Techniques Middle Aged Ovary Teratoma
        

Phenotype(s) retrieved from Orphanet

    Total: 0

HPO ID Term Frequency


Phenotype(s) retrieved from case reports

    Total: 9

HPO ID Term # of case reports
HP:0002664 Neoplasm 2
HP:0100242 Sarcoma 2
HP:0000023 Inguinal hernia 1
HP:0001824 Weight loss 1
HP:0002027 Abdominal pain 1
HP:0002315 Headache 1
HP:0002861 Melanoma 1
HP:0009792 Teratoma 1
HP:0030833 Neck pain 1


Causative gene(s) retrieved from Orphanet

    Total: 0

Gene Symbol Gene Name Entrez Gene ID