Ependymoblastoma

Ependymoblastoma is a rare type of primitive neuroectodermal tumor (PNET) that usually occurs in young children under the age of 2 and is histologically distinguished by the production of ependymoblastic rosettes. It is associated with an aggressive course and a poor prognosis.

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Narrow down the case reports

Total: 42 (papers)

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Matched Phenotype Gene Mutation MeSH

Rank (Similarity)	PMID (PMCID)
1 (35.3%)	8162155	[Neonatal brain tumor, a report of three cases]. Inoue A, Sekiguchi K, Sato S, Fujita T. Noshuyo Byori. 1994;11(1):77-83. [ Show abstract ] [ Hide abstract ]
		Facial palsy
		AFP

		Brain Neoplasms Ependymoma Fatal Outcome Females Homo sapiens Infant, Newborn Male Medulloblastoma
2 (4.0%)	30459893 (6208192)	Sellar Embryonal Tumor: A Case Report and Review of the Literature. Yakar F, Dogan , Meco C, Heper AO, Kahilogullari G. Asian J Neurosurg. 2018;13(4):1197-1201. [ Show abstract ] [ Hide abstract ]
		Primitive neuroectodermal tumor



2 (4.0%)	29432310	A Congenital Case of Ependymoblastoma: A Rare and Aggressive Brain Tumor. Grassham CD, Rady S, Foster K, SantaCruz KS, Kuttesch JF, Maxwell JR. J Pediatr Hematol Oncol. 2019;41(1):e34-e37. [ Show abstract ] [ Hide abstract ]
		Rosette


		Adult Brain Neoplasms Females Homo sapiens Infant, Newborn Neuroectodermal Tumor, Primitive Pregnancy
2 (4.0%)	28191622	Embryonal Tumor with Multilayered Rosettes in a 3-Year-Old Girl: Case Report. Govindan A, Vp M, Alapatt JP. Turk Neurosurg. 2019;29(3):451-454. [ Show abstract ] [ Hide abstract ]
		Primitive neuroectodermal tumor


		Brain Neoplasms Child, Preschool Fatal Outcome Females Homo sapiens Neoplasms, Germ Cell and Embryonal Neuroectodermal Tumor, Primitive Parietal Lobe
2 (4.0%)	26658063	Embryonal Tumor With Abundant Neuropil and True Rosettes: A Distinct Immunohistochemical Pattern. Al-Salam S, Al Alashari M. Appl Immunohistochem Mol Morphol. 2016;24(6):e41-9. [ Show abstract ] [ Hide abstract ]
		Embryonal neoplasm


		Homo sapiens Immunohistochemistry Infant Male Neoplasms, Germ Cell and Embryonal Neuropil
2 (4.0%)	26299744	[Embryonal Tumors with Multilayer Rosettes--Rare Central Nervous System Tumors in Infants]. Pleko M, Husakova K, Kaiserova E, Tichy M, Zamenik J. Klin Onkol. 2015;28(4):288-92. [ Show abstract ] [ Hide abstract ]
		Hypertension
		LIN28A

		Brain Neoplasms Child, Preschool Homo sapiens Magnetic Resonance Imaging Male Neuroectodermal Tumor, Primitive X-Ray Computed Tomography
2 (4.0%)	26252622	Embryonal tumor with multilayered rosettes of the fourth ventricle: case report. Edmonson CA, Weaver KJ, Kresak J, Pincus DW. J Neurosurg Pediatr. 2015;16(5):579-583. [ Show abstract ] [ Hide abstract ]
		Medulloepithelioma
		LIN28A


2 (4.0%)	25208992	[Primitive neuroectodermal tumor of central nervous system with features of ependymoblastoma and neuroblastoma: a clinicopathologic study of 4 cases]. Wang R, Guan W, Wu X, Zhang W, Jiang B, Ma J, Wang L. Zhonghua Bing Li Xue Za Zhi. 2014;43(6):403-7. [ Show abstract ] [ Hide abstract ]
		Primitive neuroectodermal tumor
		GFAP SYP VIM

		Antigens, Neoplasm Central Nervous System Child Females Glial Fibrillary Acidic Protein Homo sapiens Immunohistochemistry Infant Male Neuroblastoma Neuroectodermal Tumor, Primitive Synaptophysin Vimentin
2 (4.0%)	24724717	Ependymoblastoma with cystic change in a child. Ding D, Zhao A, Qiu B, Xing D, Guan G, Guo Z. J Neurosurg Pediatr. 2014;13(6):658-65. [ Show abstract ] [ Hide abstract ]
		Hypertension


		Brain Neoplasms Child, Preschool Cyst Females Homo sapiens Magnetic Resonance Imaging Neuroectodermal Tumor, Primitive X-Ray Computed Tomography
2 (4.0%)	24558755	[Are the medulloepithelioma, ependymoblastoma and embryonal tumor with multilayered rosettes the same entity?]. Ryzhova MV, Kushel' IuV, Zheludkova OG, Shishkina LV, Panina TN, Melikian AG, Zemlianskii MIu, Lemeneva NV. Zh Vopr Neirokhir Im N N Burdenko. 2013;77(6):51-5. [ Show abstract ] [ Hide abstract ]
		Medulloepithelioma
		LIN28A

		Brain Neoplasms Chromosomes, Human, Pair 19 DNA-Binding Proteins Ependymoma Homo sapiens Infant Male Neoplasm Proteins Neoplasms, Germ Cell and Embryonal Nerve Tissue Proteins Neuroectodermal Tumor, Primitive RNA-Binding Proteins

Phenotype(s) retrieved from Orphanet

Total: 0

HPO ID	Term	Frequency

Phenotype(s) retrieved from case reports

Total: 11

HPO ID	Term	# of case reports
HP:0031925	Rosette	12
HP:0030065	Primitive neuroectodermal tumor	5
HP:0002888	Ependymoma	4
HP:0030071	Medulloepithelioma	4
HP:0002898	Embryonal neoplasm	2
HP:0009792	Teratoma	2
HP:0000969	Edema	1
HP:0002176	Spinal cord compression	1
HP:0002861	Melanoma	1
HP:0100006	Neoplasm of the central nervous system	1
HP:0100242	Sarcoma	1

Causative gene(s) retrieved from Orphanet

Total: 0

Gene Symbol	Gene Name	Entrez Gene ID