NK-cell enteropathy

Natural killer (NK)-cell enteropathy is a benign NK-cell lymphoproliferative disease characterized by minor abdominal symptoms (abdominal pain, diverticulosis, constipation and reflux) due to NK cell-derived lesions in the mucosal layer of the gastrointestinal tract and often mistaken for NK or T-cell lymphoma (see these terms).



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Narrow down the case reports



Total: 1 (papers)

   


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Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)		 PMID
(PMCID)
1
(4.0%)		 29474745
 NK cell enteropathy: a case report with 10 years of indolent clinical behaviour.
Isom JA, Arroyo MR, Reddy D, Joshi-Guske P, Al-Quran SZ, Li Y, Allan RW.
Histopathology. 2018;73(2):345-350.
Abdominal pain
Females Gastrointestinal Diseases Homo sapiens Lymphoproliferative Disorders Natural Killer Cells
        

Phenotype(s) retrieved from Orphanet

    Total: 14

HPO ID Term Frequency
HP:0000969 Edema Very frequent (99-80%)
HP:0005523 Lymphoproliferative disorder Very frequent (99-80%)
HP:0100828 Increased T cell count Very frequent (99-80%)
HP:0002027 Abdominal pain Frequent (79-30%)
HP:0002014 Diarrhea Occasional (29-5%)
HP:0002019 Constipation Occasional (29-5%)
HP:0002020 Gastroesophageal reflux Occasional (29-5%)
HP:0002253 Colonic diverticula Occasional (29-5%)
HP:0002573 Hematochezia Occasional (29-5%)
HP:0002588 Duodenal ulcer Occasional (29-5%)
HP:0002592 Gastric ulcer Occasional (29-5%)
HP:0004295 Abnormality of the gastric mucosa Occasional (29-5%)
HP:0005266 Intestinal polyp Occasional (29-5%)
HP:0012425 Stercoral ulcer Occasional (29-5%)


Phenotype(s) retrieved from case reports

    Total: 0

HPO ID Term # of case reports


Causative gene(s) retrieved from Orphanet

    Total: 0

Gene Symbol Gene Name Entrez Gene ID