Somatomammotropinoma

Somatomammotropinoma is a rare, mixed, functioning pituitary adenoma characterized by the cosecretion of growth hormone and prolactin, which manifests with signs and symptoms of both acromegaly and hyperprolactinemia.



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Narrow down the case reports



Total: 1 (papers)

   


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Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)		 PMID
(PMCID)
1
(4.0%)		 27035001
 [Multiple endocrine neoplasia type 1 syndrome with three classical components and chiasm glioma: specific features of target organ lesions and a clinical observation].
Mokrysheva NG, Mamedova EO, Pigarova EA, Berezkina YA, Vorontsov AV, Azizyan VN, Grigoriev AY, Alekseeva TR, Kutin MA, Kochatkov AV, Rozhinskaya LY.
Ter Arkh. 2015;87(12):122-127.
Seizure
MEN1
Adult Females Glioma Homo sapiens Multiple Endocrine Neoplasia Type 1 Optic Chiasms Optic Nerve Neoplasms
        

Phenotype(s) retrieved from Orphanet

    Total: 60

HPO ID Term Frequency
HP:0000098 Tall stature Very frequent (99-80%)
HP:0000158 Macroglossia Very frequent (99-80%)
HP:0000179 Thick lower lip vermilion Very frequent (99-80%)
HP:0000276 Long face Very frequent (99-80%)
HP:0000280 Coarse facial features Very frequent (99-80%)
HP:0000293 Full cheeks Very frequent (99-80%)
HP:0000303 Mandibular prognathia Very frequent (99-80%)
HP:0000337 Broad forehead Very frequent (99-80%)
HP:0000400 Macrotia Very frequent (99-80%)
HP:0000445 Wide nose Very frequent (99-80%)
HP:0000830 Anterior hypopituitarism Very frequent (99-80%)
HP:0000845 Growth hormone excess Very frequent (99-80%)
HP:0000870 Prolactin excess Very frequent (99-80%)
HP:0000975 Hyperhidrosis Very frequent (99-80%)
HP:0001072 Thickened skin Very frequent (99-80%)
HP:0001176 Large hands Very frequent (99-80%)
HP:0001182 Tapered finger Very frequent (99-80%)
HP:0001386 Joint swelling Very frequent (99-80%)
HP:0001769 Broad foot Very frequent (99-80%)
HP:0001869 Deep plantar creases Very frequent (99-80%)
HP:0002758 Osteoarthritis Very frequent (99-80%)
HP:0002829 Arthralgia Very frequent (99-80%)
HP:0003859 Cortical diaphyseal thickening of the upper limbs Very frequent (99-80%)
HP:0004099 Macrodactyly Very frequent (99-80%)
HP:0006191 Deep palmar crease Very frequent (99-80%)
HP:0012378 Fatigue Very frequent (99-80%)
HP:0000044 Hypogonadotrophic hypogonadism Frequent (79-30%)
HP:0000141 Amenorrhea Frequent (79-30%)
HP:0000164 Abnormality of the dentition Frequent (79-30%)
HP:0000664 Synophrys Frequent (79-30%)
HP:0000687 Widely spaced teeth Frequent (79-30%)
HP:0000716 Depressivity Frequent (79-30%)
HP:0000739 Anxiety Frequent (79-30%)
HP:0000819 Diabetes mellitus Frequent (79-30%)
HP:0000822 Hypertension Frequent (79-30%)
HP:0001231 Abnormal fingernail morphology Frequent (79-30%)
HP:0001609 Hoarse voice Frequent (79-30%)
HP:0002007 Frontal bossing Frequent (79-30%)
HP:0002076 Migraine Frequent (79-30%)
HP:0002230 Generalized hirsutism Frequent (79-30%)
HP:0002808 Kyphosis Frequent (79-30%)
HP:0002893 Pituitary adenoma Frequent (79-30%)
HP:0003401 Paresthesia Frequent (79-30%)
HP:0003416 Spinal canal stenosis Frequent (79-30%)
HP:0006767 Pituitary prolactin cell adenoma Frequent (79-30%)
HP:0008388 Abnormal toenail morphology Frequent (79-30%)
HP:0010535 Sleep apnea Frequent (79-30%)
HP:0011760 Pituitary growth hormone cell adenoma Frequent (79-30%)
HP:0012802 Broad jaw Frequent (79-30%)
HP:0100021 Cerebral palsy Frequent (79-30%)
HP:0100540 Palpebral edema Frequent (79-30%)
HP:0100607 Dysmenorrhea Frequent (79-30%)
HP:0100829 Galactorrhea Frequent (79-30%)
HP:0000802 Impotence Occasional (29-5%)
HP:0000956 Acanthosis nigricans Occasional (29-5%)
HP:0001639 Hypertrophic cardiomyopathy Occasional (29-5%)
HP:0001653 Mitral regurgitation Occasional (29-5%)
HP:0007440 Generalized hyperpigmentation Occasional (29-5%)
HP:0100518 Dysuria Occasional (29-5%)
HP:0100786 Hypersomnia Occasional (29-5%)


Phenotype(s) retrieved from case reports

    Total: 0

HPO ID Term # of case reports


Causative gene(s) retrieved from Orphanet

    Total: 0

Gene Symbol Gene Name Entrez Gene ID