Idiopathic hypereosinophilic syndrome




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Narrow down the case reports



Total: 282 (papers)

   


(per page)
Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)		 PMID
(PMCID)
1
(45.3%)		 30626795
 [Chronic myeloid leukemia presenting with marked eosinophilia].
Haseyama Y, Takeda Y, Kumano K.
Rinsho Ketsueki. 2018;59(12):2594-2599.
Edema Splenomegaly Eosinophilia
Aged, 80 and over Antineoplastic Agents Eosinophilia Fatal Outcome Females Homo sapiens Male Philadelphia Chromosome Protein Kinase Inhibitors
2
(44.2%)		 29942409
(6011009)
 [Hypereosinophilic syndrome associated with cardiac involvement].
Zairi I, Mzoughi K.
Pan Afr Med J. 2017;28:270.
Hepatosplenomegaly Fever Hypereosinophilia
Adult Echocardiography Heart Atrium Heart Ventricle Homo sapiens Magnetic Resonance Imaging Male Thrombosis
2
(44.2%)		 29523179
(5845136)
 A young female presenting with heart failure secondary to eosinophilic myocarditis: a case report and review of the literature.
Ralapanawa DMPUK, Kumarihamy KWMPP, Sundararajah M, Jayalath WATA.
BMC Res Notes. 2018;11(1):168.
Hepatosplenomegaly Eosinophilia Low-grade fever
ABL1 FIP1L1 PDGFRA
Adult Eosinophilia Females Homo sapiens Myocarditis Young Adult
2
(44.2%)		 22374529
 [Idiopathic hypereosinophilic syndrome in a child with fever and hepatomegaly].
Morinaga S, Takaki K, Sada A, Matsui T.
Rinsho Ketsueki. 2012;53(1):83-6.
Eosinophilia Fever Hepatomegaly
CCL17 FIP1L1 IL5 NDUFB3 PDGFRA
Arylsulfonates Combination Drug Therapy Females Fever Hepatomegaly Homo sapiens Infant Mutation Oncogene Proteins, Fusion Platelet-Derived Growth Factor alpha Receptor Sulfonium Compounds mRNA Cleavage and Polyadenylation Factors
5
(43.6%)		 15492606
 Eosinophilic gastroenteritis associated with systemic lupus erythematosus.
Barbie DA, Mangi AA, Lauwers GY.
J Clin Gastroenterol. 2004;38(10):883-6.
Proteinuria Purpura Ascites
Adult Antibodies, Antinuclear Eosinophilia Females Gastroenteritis Glucocorticoids Homo sapiens Intestines, Small Laparoscopy Laparotomy Lupus Erythematosus, Systemic
6
(43.3%)		 6519406
 [Icterus disclosing pancreatic involvement in idiopathic hypereosinophilic syndrome].
Eugene C, Gury B, Bergue A, Quevauvilliers J.
Gastroenterol Clin Biol. 1984;8(12):966-9.
Jaundice Eosinophilia Pleural effusion
IGHE
Adult Duodenum Echocardiography Electromyography Eosinophilia Homo sapiens Icterus Male Pancreas Pancreatic Diseases Syndrome
7
(40.5%)		 28263223
 Hypereosinophilic Syndrome After Liver Transplantation: A Case Report and a Review of the Literature.
Aulbert W, Kobbe R, Breuer C, Briem-Richter A, Schafer H, Brinkert F, Dettmar A, Kemper MJ, Grabhorn E.
Transplantation. 2017;101(5):e166-e169.
Eosinophilia Recurrent fever Biliary atresia
Child Homo sapiens Male Postoperative Complications
8
(39.7%)		 1958137
 [A case of idiopathic hypereosinophilic syndrome (HES) complicated by pulmonary infarction].
Koike R, Yoshida S, Takahashi H.
Arerugi. 1991;40(9):1232-8.
Cyanosis Eosinophilia Pleural effusion
Adult Cardiolipins Eosinophilia Females Homo sapiens Lupus Coagulation Inhibitor Pulmonary Embolism
9
(39.1%)		 14992769
 [Idiopathic hypereosinophilic syndrome: a case report in an infant].
Leblond P, Lepers S, Thebaud E, Mazingue F, Lambilliotte A, Fournier M, Nelken B.
Arch Pediatr. 2004;11(3):219-22.
Splenomegaly Eosinophilia
Homo sapiens Infant Male
9
(39.1%)		 10800164
 Cytogenetic and molecular cytogenetic characterization of 6 new cases of idiopathic hypereosinophilic syndrome.
Bigoni R, Cuneo A, Roberti MG, Milani R, Bardi A, Cavazzini F, Minotto C, Castoldi G.
Haematologica. 2000;85(5):486-91.
Splenomegaly Eosinophilia
ABL1 BCR
Adult Bone Marrow Cells Chromosome Aberrations Clone Cells Cytogenetic Analysis Females Fluorescent in Situ Hybridization Homo sapiens Male Middle Aged
        

Phenotype(s) retrieved from Orphanet

    Total: 78

HPO ID Term Frequency
HP:0001880 Eosinophilia Very frequent (99-80%)
HP:0000980 Pallor Frequent (79-30%)
HP:0001903 Anemia Frequent (79-30%)
HP:0001945 Fever Frequent (79-30%)
HP:0001974 Leukocytosis Frequent (79-30%)
HP:0002098 Respiratory distress Frequent (79-30%)
HP:0002863 Myelodysplasia Frequent (79-30%)
HP:0003270 Abdominal distention Frequent (79-30%)
HP:0031323 Myocardial eosinophilic infiltration Frequent (79-30%)
HP:0100724 Hypercoagulability Frequent (79-30%)
HP:0000622 Blurred vision Occasional (29-5%)
HP:0000708 Behavioral abnormality Occasional (29-5%)
HP:0000726 Dementia Occasional (29-5%)
HP:0000964 Eczema Occasional (29-5%)
HP:0000965 Cutis marmorata Occasional (29-5%)
HP:0000989 Pruritus Occasional (29-5%)
HP:0001019 Erythroderma Occasional (29-5%)
HP:0001025 Urticaria Occasional (29-5%)
HP:0001217 Clubbing Occasional (29-5%)
HP:0001250 Seizures Occasional (29-5%)
HP:0001289 Confusion Occasional (29-5%)
HP:0001298 Encephalopathy Occasional (29-5%)
HP:0001324 Muscle weakness Occasional (29-5%)
HP:0001347 Hyperreflexia Occasional (29-5%)
HP:0001369 Arthritis Occasional (29-5%)
HP:0001386 Joint swelling Occasional (29-5%)
HP:0001433 Hepatosplenomegaly Occasional (29-5%)
HP:0001508 Failure to thrive Occasional (29-5%)
HP:0001635 Congestive heart failure Occasional (29-5%)
HP:0001644 Dilated cardiomyopathy Occasional (29-5%)
HP:0001727 Thromboembolic stroke Occasional (29-5%)
HP:0001733 Pancreatitis Occasional (29-5%)
HP:0001744 Splenomegaly Occasional (29-5%)
HP:0001785 Ankle swelling Occasional (29-5%)
HP:0001873 Thrombocytopenia Occasional (29-5%)
HP:0001894 Thrombocytosis Occasional (29-5%)
HP:0002013 Vomiting Occasional (29-5%)
HP:0002015 Dysphagia Occasional (29-5%)
HP:0002024 Malabsorption Occasional (29-5%)
HP:0002027 Abdominal pain Occasional (29-5%)
HP:0002028 Chronic diarrhea Occasional (29-5%)
HP:0002094 Dyspnea Occasional (29-5%)
HP:0002099 Asthma Occasional (29-5%)
HP:0002113 Pulmonary infiltrates Occasional (29-5%)
HP:0002170 Intracranial hemorrhage Occasional (29-5%)
HP:0002202 Pleural effusion Occasional (29-5%)
HP:0002204 Pulmonary embolism Occasional (29-5%)
HP:0002206 Pulmonary fibrosis Occasional (29-5%)
HP:0002326 Transient ischemic attack Occasional (29-5%)
HP:0002354 Memory impairment Occasional (29-5%)
HP:0002583 Colitis Occasional (29-5%)
HP:0002829 Arthralgia Occasional (29-5%)
HP:0002910 Elevated hepatic transaminase Occasional (29-5%)
HP:0003202 Skeletal muscle atrophy Occasional (29-5%)
HP:0003326 Myalgia Occasional (29-5%)
HP:0003401 Paresthesia Occasional (29-5%)
HP:0003474 Sensory impairment Occasional (29-5%)
HP:0004302 Functional motor deficit Occasional (29-5%)
HP:0005115 Supraventricular arrhythmia Occasional (29-5%)
HP:0005547 Myeloproliferative disorder Occasional (29-5%)
HP:0006253 Swelling of proximal interphalangeal joints Occasional (29-5%)
HP:0006580 Portal fibrosis Occasional (29-5%)
HP:0008872 Feeding difficulties in infancy Occasional (29-5%)
HP:0008940 Generalized lymphadenopathy Occasional (29-5%)
HP:0009830 Peripheral neuropathy Occasional (29-5%)
HP:0011123 Inflammatory abnormality of the skin Occasional (29-5%)
HP:0011897 Neutrophilia Occasional (29-5%)
HP:0011974 Myelofibrosis Occasional (29-5%)
HP:0012735 Cough Occasional (29-5%)
HP:0025289 Cervical lymphadenopathy Occasional (29-5%)
HP:0030151 Cholangitis Occasional (29-5%)
HP:0030880 Raynaud phenomenon Occasional (29-5%)
HP:0100665 Angioedema Occasional (29-5%)
HP:0100749 Chest pain Occasional (29-5%)
HP:0200029 Vasculitis in the skin Occasional (29-5%)
HP:0200034 Papule Occasional (29-5%)
HP:0200036 Skin nodule Occasional (29-5%)
HP:0200123 Chronic hepatitis Occasional (29-5%)


Phenotype(s) retrieved from case reports

    Total: 78

HPO ID Term # of case reports
HP:0001880 Eosinophilia 58
HP:0032061 Hypereosinophilia 24
HP:0012819 Myocarditis 7
HP:0001909 Leukemia 6
HP:0009830 Peripheral neuropathy 6
HP:0100584 Endocarditis 5
HP:0001298 Encephalopathy 4
HP:0001297 Stroke 3
HP:0001907 Thromboembolism 3
HP:0001945 Fever 3
HP:0002204 Pulmonary embolism 3
HP:0006685 Endocardial fibrosis 3
HP:0012115 Hepatitis 3
HP:0000989 Pruritus 2
HP:0001370 Rheumatoid arthritis 2
HP:0001733 Pancreatitis 2
HP:0002099 Asthma 2
HP:0002202 Pleural effusion 2
HP:0002583 Colitis 2
HP:0002878 Respiratory failure 2
HP:0030242 Portal vein thrombosis 2
HP:0100614 Myositis 2
HP:0200123 Chronic hepatitis 2
HP:0000726 Dementia 1
HP:0000819 Diabetes mellitus 1
HP:0000822 Hypertension 1
HP:0000846 Adrenal insufficiency 1
HP:0000952 Jaundice 1
HP:0001019 Erythroderma 1
HP:0001289 Confusion 1
HP:0001369 Arthritis 1
HP:0001433 Hepatosplenomegaly 1
HP:0001541 Ascites 1
HP:0001635 Congestive heart failure 1
HP:0001670 Asymmetric septal hypertrophy 1
HP:0001698 Pericardial effusion 1
HP:0001701 Pericarditis 1
HP:0001718 Mitral stenosis 1
HP:0001873 Thrombocytopenia 1
HP:0002014 Diarrhea 1
HP:0002027 Abdominal pain 1
HP:0002090 Pneumonia 1
HP:0002094 Dyspnea 1
HP:0002107 Pneumothorax 1
HP:0002206 Pulmonary fibrosis 1
HP:0002240 Hepatomegaly 1
HP:0002563 Constrictive pericarditis 1
HP:0002586 Peritonitis 1
HP:0002621 Atherosclerosis 1
HP:0002625 Deep venous thrombosis 1
HP:0002664 Neoplasm 1
HP:0002716 Lymphadenopathy 1
HP:0002721 Immunodeficiency 1
HP:0002835 Aspiration 1
HP:0002902 Hyponatremia 1
HP:0002955 Granulomatosis 1
HP:0003326 Myalgia 1
HP:0005110 Atrial fibrillation 1
HP:0005180 Tricuspid regurgitation 1
HP:0005263 Gastritis 1
HP:0005912 Biliary atresia 1
HP:0007178 Motor polyneuropathy 1
HP:0010783 Erythema 1
HP:0012089 Arteritis 1
HP:0012393 Allergy 1
HP:0012735 Cough 1
HP:0025289 Cervical lymphadenopathy 1
HP:0030149 Cardiogenic shock 1
HP:0030882 Coronary artery aneurysm 1
HP:0031273 Shock 1
HP:0031352 Chest tightness 1
HP:0031780 Eosinophilic ascites 1
HP:0100724 Hypercoagulability 1
HP:0100726 Kaposi's sarcoma 1
HP:0100749 Chest pain 1
HP:0100820 Glomerulopathy 1
HP:0200042 Skin ulcer 1
HP:0200120 Chronic active hepatitis 1


Causative gene(s) retrieved from Orphanet

    Total: 0

Gene Symbol Gene Name Entrez Gene ID