Acrokeratoelastoidosis of Costa

A rare dermatosis characterized by small, firm papules or plaques (resembling warts) on the sides of the hands and feet. These stationary and asymptomatic lesions appear generally at puberty, or sometimes later



Input patient's signs and symptoms


Narrow down the case reports



Total: 7 (papers)

   


(per page)
Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)		 PMID
(PMCID)
1
(17.5%)		 8305752
 Marginal papular acrokeratodermas: a unified nosography for focal acral hyperkeratosis, acrokeratoelastoidosis and related disorders.
Rongioletti F, Betti R, Crosti C, Rebora A.
Dermatology. 1994;188(1):28-31.
Calcinosis
Females Hand Dermatoses Homo sapiens Keratosis Middle Aged Skin
2
(4.0%)		 25184932
(4155971)
 Case for diagnosis.
Sano DT, Melo LV, Tebcherani AJ, Sanchez AP.
An Bras Dermatol. 2014;89(5):835-6.
Papule
Adult Biopsy Dermis Differential Diagnosis Females Homo sapiens Keratoderma, Palmoplantar
2
(4.0%)		 12220276
 Acrokeratoelastoidosis.
Hu W, Cook TF, Vicki GJ, Glaser DA.
Pediatr Dermatol. 2002;19(4):320-2.
Hyperkeratosis
Dermatologic Agents Elastic Tissue Females Follow-Up Studies Health Risk Assessment Homo sapiens Immunohistochemistry Keratoderma, Palmoplantar Severity of Illness Index
2
(4.0%)		 11422170
 Acquired crateriform hyperkeratotic papules of the lower limbs: an unusual variant of acrokeratoelastoidosis of Costa.
Helbling I, Tucker SC, Chalmers RJ.
Clin Exp Dermatol. 2001;26(3):263-5.
Hyperkeratotic papule
FAH
Homo sapiens Keratosis Leg Dermatoses Male Terminology as Topic
2
(4.0%)		 10460303
 [Focal acral hyperkeratosis].
Hafner O, Gerstel C.
Hautarzt. 1999;50(8):586-9.
Hyperkeratotic papule
Biopsy Differential Diagnosis Elastic Tissue Females Homo sapiens Keratoderma, Palmoplantar Middle Aged Skin
2
(4.0%)		 9870680
 Acrokeratoelastoidosis of Costa: a primary disease of the elastic tissue?
Fiallo P, Pesce C, Brusasco A, Nunzi E.
J Cutan Pathol. 1998;25(10):580-2.
Hyperkeratosis
Adult Connective Tissue Diseases Elastic Tissue Females Foot Dermatoses Hand Dermatoses Homo sapiens Keratosis Skin
2
(4.0%)		 8304711
 [Costa acro-kerato-elastoidosis].
Boudghene-Stambouli O, Merad-Boudia A, Benkalfat MR, Khedim A.
Ann Dermatol Venereol. 1993;120(8):539-41.
Hyperhidrosis
Adult Elastic Tissue Females Homo sapiens Keratoderma, Palmoplantar
        

Phenotype(s) retrieved from Orphanet

    Total: 7

HPO ID Term Frequency
HP:0000962 Hyperkeratosis Very frequent (99-80%)
HP:0001482 Subcutaneous nodule Very frequent (99-80%)
HP:0200016 Acrokeratosis Very frequent (99-80%)
HP:0200034 Papule Very frequent (99-80%)
HP:0200043 Verrucae Very frequent (99-80%)
HP:0000975 Hyperhidrosis Frequent (79-30%)
HP:0001597 Abnormality of the nail Frequent (79-30%)


Phenotype(s) retrieved from case reports

    Total: 3

HPO ID Term # of case reports
HP:0003761 Calcinosis 1
HP:0045059 Hyperkeratotic papule 1
HP:0200034 Papule 1


Causative gene(s) retrieved from Orphanet

    Total: 0

Gene Symbol Gene Name Entrez Gene ID