Isosporiasis

Isosporiasis (also known as cystoisosporiasis) is an exclusively human parasitosis occurring mainly in the tropics and subtropics, due to infection with <i>Isospora belli</i> (through ingestion of contaminated food), that is frequently asymptomatic or that can cause fever and diarrhea, but that is usually a self-limiting condition in the immunocompetent. HIV-positive individuals are particularly at risk of suffering from symptomatic isosporiasis and can manifest with a more severe clinical course of chronic diarrhea and severe weight loss.



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Total: 33 (papers)

   


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Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)		 PMID
(PMCID)
2
(4.0%)		 23295886
 Common variable immunodeficiency and isosporiasis: first report case.
Silva GB, Fernandes KP, Segundo GR.
Rev Soc Bras Med Trop. 2012;45(6):768-9.
Opportunistic infection
Common Variable Immunodeficiency Diarrhea Feces Females Giardiasis Homo sapiens Isosporiasis Middle Aged Opportunistic Infections Severity of Illness Index
2
(4.0%)		 21458380
 Molecular diagnosis of cystoisosporiasis using extended-range PCR screening.
Murphy SC, Hoogestraat DR, Sengupta DJ, Prentice J, Chakrapani A, Cookson BT.
J Mol Diagn. 2011;13(3):359-62.
Diarrhea
Adult DNA, Ribosomal Spacer HIV Infections Homo sapiens Immunocompromised Host Isospora Isosporiasis Male Polymerase Chain Reaction Ribosomal RNA
2
(4.0%)		 20422140
 Severe diarrhea due to Isospora belli in a patient with thymoma.
Meamar AR, Rezaian M, Mirzaei AZ, Zahabiun F, Faghihi AH, Oormazdi H, Kia EB.
J Microbiol Immunol Infect. 2009;42(6):526-9.
Diarrhea
Adult Diarrhea Feces Homo sapiens Isospora Isosporiasis Male Thymoma Thymus Neoplasms
2
(4.0%)		 19447468
 Isospora cholangiopathy: case study with histologic characterization and molecular confirmation.
Walther Z, Topazian MD.
Hum Pathol. 2009;40(9):1342-6.
Diarrhea
Acquired Immunodeficiency Syndrome Adult Animals Anti-Infective Agents Antiparasitic Agents Bile Ducts, Extrahepatic Biopsy Cholangitis, Sclerosing Endoscopic Retrograde Cholangiopancreatography Homo sapiens Isospora Isosporiasis Male Polymerase Chain Reaction Trimethoprim-Sulfamethoxazole Combination
2
(4.0%)		 18338696
 Isospora belli infection in a malnourished child.
Kochhar A, Saxena S, Malhotra VL, Deb M.
J Commun Dis. 2007;39(2):141-3.
Weight loss
Animals Anti-Infective Agents Child Diarrhea Females Homo sapiens Immunocompromised Host Isospora Isosporiasis Parasite Egg Count Trimethoprim-Sulfamethoxazole Combination
2
(4.0%)		 17580223
 A rare diarrheic parasite in a liver transplant patient: Isospora belli.
Atambay M, Bayraktar MR, Kayabas U, Yilmaz S, Bayindir Y.
Transplant Proc. 2007;39(5):1693-5.
Diarrhea
Adult Animals Antiparasitic Agents Females Homo sapiens Immunocompromised Host Isospora Isosporiasis Postoperative Complications Trimethoprim-Sulfamethoxazole Combination
2
(4.0%)		 15973029
 Refractory isosporiasis.
Malik S, Samantaray JC, Bagga A, Das A.
Indian J Pediatr. 2005;72(5):437-9.
Diarrhea
Animals Anti-Infective Agents Child, Preschool Diarrhea Fatal Outcome Feces Homo sapiens Isospora Isosporiasis Male Trimethoprim-Sulfamethoxazole Combination
2
(4.0%)		 14616755
 Isospora belli infection in a patient with non-Hodgkin's lymphoma.
Resiere D, Vantelon JM, Bouree P, Chachaty E, Nitenberg G, Blot F.
Clin Microbiol Infect. 2003;9(10):1065-7.
Leukemia
Adult Animals Antiprotozoal Agents Diarrhea Feces France Homo sapiens Isospora Isosporiasis Lymphoma, Non-Hodgkin Male Mali Trimethoprim-Sulfamethoxazole Combination
2
(4.0%)		 12935734
 Gastrointestinal cryptosporidiosis in a puppy.
Miller DL, Liggett A, Radi ZA, Branch LO.
Vet Parasitol. 2003;115(3):199-204.
Diarrhea
Actins Animals Canis familiaris Cryptosporidiosis Cryptosporidium DNA, Protozoan Dog Diseases Females Gastrointestinal Diseases Intestinal Mucosa Phylogeny Polymerase Chain Reaction RNA, Ribosomal, 18S
2
(4.0%)		 12578164
 Recurrent isosporiasis over a decade in an immunocompetent host successfully treated with pyrimethamine.
Jongwutiwes S, Sampatanukul P, Putaporntip C.
Scand J Infect Dis. 2002;34(11):859-62.
Intermittent diarrhea
Animals Anti-Infective Agents Antiprotozoal Agents Drug Administration Schedule Homo sapiens Immunocompetence Isospora Isosporiasis Male Middle Aged Time Factors Trimethoprim-Sulfamethoxazole Combination
        

Phenotype(s) retrieved from Orphanet

    Total: 0

HPO ID Term Frequency


Phenotype(s) retrieved from case reports

    Total: 8

HPO ID Term # of case reports
HP:0002014 Diarrhea 8
HP:0001824 Weight loss 3
HP:0001082 Cholecystitis 1
HP:0002024 Malabsorption 1
HP:0002027 Abdominal pain 1
HP:0002028 Chronic diarrhea 1
HP:0004326 Cachexia 1
HP:0031690 Opportunistic infection 1


Causative gene(s) retrieved from Orphanet

    Total: 0

Gene Symbol Gene Name Entrez Gene ID