Dengue fever

Dengue fever (DF), caused by dengue virus, is an arboviral disease characterized by an initial non-specific febrile illness that can sometimes progress to more severe forms manifesting capillary leakage and hemorrhage (dengue hemorrhagic fever, or DHF) and shock (dengue shock syndrome, or DSS).



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Narrow down the case reports



Total: 426 (papers)

  


(per page)
Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)
PMID
(PMCID)
1
(55.1%)
11414404
Morbitz type I second degree AV block during recovery from dengue hemorrhagic fever.
Khongphatthallayothin A, Chotivitayatarakorn P, Somchit S, Mitprasart A, Sakolsattayadorn S, Thisyakorn C.
Southeast Asian J Trop Med Public Health. 2000;31(4):642-5.
Anemia Fever Hepatomegaly
Child Electrocardiography Females Heart Block Homo sapiens Male Severe Dengue
2
(49.1%)
24174736
(3800419)
Acute gingival bleeding as a complication of dengue hemorrhagic fever.
Khan S, Gupta ND, Maheshwari S.
J Indian Soc Periodontol. 2013;17(4):520-2.
Anemia Fever Ecchymosis
3
(48.9%)
29485843
Pathogenic Compound Heterozygous Mutations in a Mexican Mestizo Patient with Niemann-Pick Disease Type B.
Velarde-Felix JS, Osuna-Ramos JF, Sanchez-Leyva MG, Rios Burgueno ER, Monroy Arellano LM.
Genet Couns. 2016;27(2):211-7.
Hepatosplenomegaly Anemia
SMPD1
c|SUB|A|1343|G;RS#:747143343 c|SUB|C|1426|T;RS#:182812968 p|SUB|R|474|W;RS#:182812968 p|SUB|R|476|W;RS#:182812968 p|SUB|Y|446|C;RS#:747143343 p|SUB|Y|448|C;RS#:747143343 rs182812968 rs747143343
Adult Females Homo sapiens Mexico Niemann-Pick Disease, Type B Young Adult
3
(48.9%)
24678156
(3943118)
Spontaneous splenic rupture: A rare presentation of dengue fever.
Mukhopadhyay M, Chatterjee N, Maity P, Patar K.
Indian J Crit Care Med. 2014;18(2):110-2.
Hepatosplenomegaly Anemia
5
(46.2%)
27051578
(4802816)
Fever in a traveler returning from the Amazon. Do not forget hepatitis A.
Cunha BA, Teper RS, Raza M.
IDCases. 2016;4:18-9.
Splenomegaly Thrombocytopenia Fever Hepatitis
5
(46.2%)
8426957
[Imported dengue fever following a stay in the tropics].
Hasler C, Schnorf H, Enderlin N, Gyr K.
Schweiz Med Wochenschr. 1993;123(4):120-4.
Epistaxis Splenomegaly Fever Hepatitis
Adult Dengue Fever Females Hemagglutination Inhibition Tests Homo sapiens Switzerland Thailand
7
(46.0%)
18434933
Dengue virus infection in late pregnancy and transmission to the infants.
Phongsamart W, Yoksan S, Vanaprapa N, Chokephaibulkit K.
Pediatr Infect Dis J. 2008;27(6):500-4.
Petechiae Fever Hepatomegaly
Adult Antibodies, Viral Dengue Fever Dengue Virus Females Follow-Up Studies Homo sapiens Infant Infant, Newborn Pregnancy Pregnancy Complications, Infectious RNA, Viral Reverse Transcriptase Polymerase Chain Reaction
8
(44.2%)
24452132
(5779429)
Fatal hemophagocytic lymphohistiocytosis associated with locally acquired dengue virus infection - New Mexico and Texas, 2012.
Sharp TM, Gaul L, Muehlenbachs A, Hunsperger E, Bhatnagar J, Lueptow R, Santiago GA, Munoz-Jordan JL, Blau DM, Ettestad P, Bissett JD, Ledet SC, Zaki SR, Tomashek KM.
MMWR Morb Mortal Wkly Rep. 2014;63(3):49-54.
Hepatosplenomegaly Pancytopenia Fever
Dengue Fever Fatal Outcome Females Homo sapiens Lymphohistiocytosis, Hemophagocytic Middle Aged New Mexico Texas
8
(44.2%)
19522310
[Case of imported scrub typhus contracted in Myanmar].
Matsumura Y, Shimizu T.
Kansenshogaku Zasshi. 2009;83(3):256-60.
Hepatosplenomegaly Thrombocytopenia Fever
Homo sapiens Japan Male Middle Aged Myanmar Scrub Typhus
8
(44.2%)
14700159
Vertical transmission of dengue infection in Thai infants: two case reports.
Chotigeat U, Kalayanarooj S, Nisalak A.
J Med Assoc Thai. 2003;86 Suppl 3:S628-32.
Thrombocytopenia Fever Hepatomegaly
Adult Dengue Fever Females Homo sapiens Infant, Newborn Male Pregnancy Thailand
        

Phenotype(s) retrieved from Orphanet

    Total: 22

HPO ID Term Frequency
HP:0001945 Fever Very frequent (99-80%)
HP:0002315 Headache Very frequent (99-80%)
HP:0000988 Skin rash Frequent (79-30%)
HP:0000989 Pruritus Frequent (79-30%)
HP:0002027 Abdominal pain Frequent (79-30%)
HP:0002829 Arthralgia Frequent (79-30%)
HP:0000225 Gingival bleeding Occasional (29-5%)
HP:0000421 Epistaxis Occasional (29-5%)
HP:0000967 Petechiae Occasional (29-5%)
HP:0000978 Bruising susceptibility Occasional (29-5%)
HP:0001254 Lethargy Occasional (29-5%)
HP:0001342 Cerebral hemorrhage Occasional (29-5%)
HP:0001541 Ascites Occasional (29-5%)
HP:0001873 Thrombocytopenia Occasional (29-5%)
HP:0001882 Leukopenia Occasional (29-5%)
HP:0002014 Diarrhea Occasional (29-5%)
HP:0002017 Nausea and vomiting Occasional (29-5%)
HP:0002239 Gastrointestinal hemorrhage Occasional (29-5%)
HP:0002240 Hepatomegaly Occasional (29-5%)
HP:0002615 Hypotension Occasional (29-5%)
HP:0003075 Hypoproteinemia Occasional (29-5%)
HP:0006543 Cardiorespiratory arrest Occasional (29-5%)


Phenotype(s) retrieved from case reports

    Total: 125

HPO ID Term # of case reports
HP:0001945 Fever 82
HP:0031273 Shock 27
HP:0001873 Thrombocytopenia 19
HP:0001298 Encephalopathy 11
HP:0003201 Rhabdomyolysis 11
HP:0012486 Myelitis 9
HP:0003326 Myalgia 7
HP:0001735 Acute pancreatitis 6
HP:0002315 Headache 6
HP:0002829 Arthralgia 6
HP:0012223 Splenic rupture 6
HP:0001082 Cholecystitis 5
HP:0001919 Acute kidney injury 5
HP:0012115 Hepatitis 5
HP:0000505 Visual impairment 4
HP:0001882 Leukopenia 4
HP:0002027 Abdominal pain 4
HP:0002170 Intracranial hemorrhage 4
HP:0012156 Hemophagocytosis 4
HP:0100614 Myositis 4
HP:0000572 Visual loss 3
HP:0000618 Blindness 3
HP:0002014 Diarrhea 3
HP:0002615 Hypotension 3
HP:0002721 Immunodeficiency 3
HP:0012819 Myocarditis 3
HP:0030150 Plasmacytosis 3
HP:0100758 Gangrene 3
HP:0000020 Urinary incontinence 2
HP:0000099 Glomerulonephritis 2
HP:0000112 Nephropathy 2
HP:0000123 Nephritis 2
HP:0000603 Central scotoma 2
HP:0000952 Jaundice 2
HP:0001138 Optic neuropathy 2
HP:0001250 Seizures 2
HP:0001251 Ataxia 2
HP:0001698 Pericardial effusion 2
HP:0001876 Pancytopenia 2
HP:0002013 Vomiting 2
HP:0002181 Cerebral edema 2
HP:0002480 Hepatic encephalopathy 2
HP:0002902 Hyponatremia 2
HP:0003470 Paralysis 2
HP:0100282 Acute colitis 2
HP:0100646 Thyroiditis 2
HP:0100653 Optic neuritis 2
HP:0000016 Urinary retention 1
HP:0000421 Epistaxis 1
HP:0000488 Retinopathy 1
HP:0000501 Glaucoma 1
HP:0000508 Ptosis 1
HP:0000509 Conjunctivitis 1
HP:0000544 External ophthalmoplegia 1
HP:0000575 Scotoma 1
HP:0000704 Periodontitis 1
HP:0000829 Hypoparathyroidism 1
HP:0000836 Hyperthyroidism 1
HP:0000873 Diabetes insipidus 1
HP:0000967 Petechiae 1
HP:0000969 Edema 1
HP:0000979 Purpura 1
HP:0000988 Skin rash 1
HP:0001085 Papilledema 1
HP:0001260 Dysarthria 1
HP:0001271 Polyneuropathy 1
HP:0001281 Tetany 1
HP:0001287 Meningitis 1
HP:0001300 Parkinsonism 1
HP:0001336 Myoclonus 1
HP:0001369 Arthritis 1
HP:0001399 Hepatic failure 1
HP:0001541 Ascites 1
HP:0001649 Tachycardia 1
HP:0001662 Bradycardia 1
HP:0001678 Atrioventricular block 1
HP:0001701 Pericarditis 1
HP:0001875 Neutropenia 1
HP:0001888 Lymphopenia 1
HP:0001903 Anemia 1
HP:0001944 Dehydration 1
HP:0002018 Nausea 1
HP:0002078 Truncal ataxia 1
HP:0002090 Pneumonia 1
HP:0002140 Ischemic stroke 1
HP:0002148 Hypophosphatemia 1
HP:0002202 Pleural effusion 1
HP:0002248 Hematemesis 1
HP:0002583 Colitis 1
HP:0002586 Peritonitis 1
HP:0002653 Bone pain 1
HP:0002835 Aspiration 1
HP:0002901 Hypocalcemia 1
HP:0005268 Spontaneous abortion 1
HP:0005305 Cerebral venous thrombosis 1
HP:0005521 Disseminated intravascular coagulation 1
HP:0006562 Viral hepatitis 1
HP:0006597 Diaphragmatic paralysis 1
HP:0008682 Acute tubular necrosis 1
HP:0009830 Peripheral neuropathy 1
HP:0010543 Opsoclonus 1
HP:0011458 Abdominal symptom 1
HP:0011506 Choroidal neovascularization 1
HP:0011709 Atrioventricular dissociation 1
HP:0011854 Hemoperitoneum 1
HP:0011921 Exudative pleural effusion 1
HP:0011974 Myelofibrosis 1
HP:0012109 Angle closure glaucoma 1
HP:0012378 Fatigue 1
HP:0012597 Heavy proteinuria 1
HP:0012636 Retinal vein occlusion 1
HP:0020071 Viremia 1
HP:0025337 Red eye 1
HP:0025342 Central retinal artery occlusion 1
HP:0025615 Abscess 1
HP:0031364 Ecchymosis 1
HP:0031864 Bacteremia 1
HP:0031931 Ocular flutter 1
HP:0040223 Pulmonary hemorrhage 1
HP:0045073 Serositis 1
HP:0100279 Ulcerative colitis 1
HP:0100519 Anuria 1
HP:0100532 Scleritis 1
HP:0100806 Sepsis 1
HP:0100827 Lymphocytosis 1


Causative gene(s) retrieved from Orphanet

    Total: 0

Gene Symbol Gene Name Entrez Gene ID