Hydrops fetalis

Hydrops fetalis is a severe and challenging fetal condition usually defined as the excessive accumulation of fetal fluid within the fetal extravascular compartments and body cavities that manifests as edema, pleural and pericardial effusion and ascites. It is the end-stage of a wide variety of disorders. The cause may be immunologic (immune hydrops fetalis, IHF) or non immunologic (non-immune hydrops fetalis, NIHF), depending on the presence or absence of maternal antibodies against fetal red cell antigens (ABO incompatibility or rhesus (Rh) incompatibility).

Splenomegaly

Abnormal increased size of the spleen.

Total: 2

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PMID (PMCID)
11041442	FEMALE	Infant, Newborn
	Perinatal lethal form of Gaucher's disease presenting with hemosiderosis.
	Sharma R, Hudak ML, Perszyk AA, Premachandra BR, Li H, Monteiro C. Am J Perinatol. 2000;17(4):201-6.
	A term infant with hydrops fetalis presented with hypotonia, massive splenomegaly, renal failure, and severe hyperferritinemia.
7991512	FEMALE	Infant, Newborn
	Prenatally diagnosed non-immune hydrops caused by congenital transient leukaemia.
	Donnenfeld AE, Scott SC, Henselder-Kimmel M, Dampier CD. Prenat Diagn. 1994;14(8):721-4.
	We present a case of prenatally diagnosed fetal hydrops accompanied by splenomegaly and an enlarged, echogenic liver in a fetus identified with CTL after birth.