Aspergillosis

A rare infectious disease caused by inhalation of the opportunistic fungus <i>aspergillus</i> that can lead to the following manifestations: allergic bronchopulmonary aspergillosis (ABPA), aspergilloma, chronic necrotizing pulmonary aspergillosis (CNPA), and invasive aspergillosis (IA). Aspergilloma occurs in patients with cavitary lung disease and results in a fungal mass with variable clinical presentations from asymptomatic to life-threatening (massive hemoptysis). CNPA manifests as subacute pneumonia in patients with underlying disease. IA is disseminated aspergillosis that eventually invades other organs. Cutaneous aspergillosis is usually the dermatological manifestation of IA that manifests as erythematous-to-violaceous plaques or papules, often characterized by a central necrotic ulcer or eschar.

Osteomyelitis

Osteomyelitis is an inflammatory process accompanied by bone destruction and caused by an infecting microorganism.

Total: 26

(per page)

PMID (PMCID)
30457728	OTHER
	[Chronic granulomatous disease: multiple infections as clinical presentation. Pediatric case report].
	Maydana M, Cabanillas D, Regairaz L, Bastons S, Uriarte V, Garcia M, Sosa MF, Vinuesa M, Del Palacio P, Morales J. Arch Argent Pediatr. 2018;116(6):e744-e748.
	We describe here a case of a 1-year-old boy with chronic granulomatous disease and invasive pulmonary aspergillosis, Serratia marcescens osteomyelitis and Enterobacter cloacae cervical granuloma.
27721629 (5051312)	OTHER
	Fungal osteomyelitis of maxillofacial bones: Rare presentation.
	Urs AB, Singh H, Mohanty S, Sharma P. J Oral Maxillofac Pathol. 2016;20(3):546.
	The current series showed five cases of fungal osteomyelitis which included candidal osteomyelitis, aspergillosis and mucormycosis with slight predominance of maxilla over mandible.
27721629 (5051312)	OTHER
	Fungal osteomyelitis of maxillofacial bones: Rare presentation.
	Urs AB, Singh H, Mohanty S, Sharma P. J Oral Maxillofac Pathol. 2016;20(3):546.
	The current series showed five cases of fungal osteomyelitis which included candidal osteomyelitis, aspergillosis and mucormycosis with slight predominance of maxilla over mandible.
28681028 (5490289)	OTHER
	Osteomyelitis and lung abscess due to Aspergillus fumigatus in a chronic granulomatous disease patient.
	Mamishi S, Zomorodian K, Saadat F, Jalali SZ, Geramishoar M. Curr Med Mycol. 2016;2(3):37-41.
	Invasive aspergillosis in this patient with pneumonia, lung abscess, and osteomyelitis of the ribs was not initially treated with amphotericin B (Am B) and recombinant interferon-gamma.
25221965	MALE	Middle Aged
	Lumbar Aspergillus osteomyelitis mimicking pyogenic osteomyelitis in an immunocompetent adult.
	Yoon KW, Kim YJ. Br J Neurosurg. 2015;29(2):277-9.
	The authors report a case of lumbar Aspergillus osteomyelitis in an immunocompetent adult and reviewed previously described cases of spinal aspergillosis.
25301635 (4200168)	MALE	Adult
	Disseminated Aspergillus flavus following septic arthritis in an immunocompetent patient: a case report.
	Tiwari V, Khatri K, Khan SA, Nath D. BMC Res Notes. 2014;7:709.
	Aspergillosis is a rare cause of osteomyelitis and septic arthritis.
24049367 (3766334)	OTHER
	Case report of Aspergillus osteomyelitis of the ribs in an immunocompetent patient.
	D'sa SR, Singh S, Satyendra S, Mathews P. J Glob Infect Dis. 2013;5(3):118-20.
	Amongst all the reported cases of invasive aspergillosis the incidence of osteomyelitis is less than three percent.
22588549	FEMALE
	Pseudotumoral cutaneous aspergillosis in chronic granulomatous disease, report of a pediatric case.
	Khemiri M, El fekih N, Borgi A, Kharfi M, Boubaker S, Barsaoui S. Am J Dermatopathol. 2012;34(7):749-52.
	We describe an unusual case of invasive cutaneous aspergillosis presented as a large burgeoning tumor in a 4-year-old girl with CGD who underwent surgical treatment for bifocal osteomyelitis of the left leg.
21873929	MALE
	Successful treatment of Aspergillus flavus spondylodiscitis with epidural abscess in a patient with chronic granulomatous disease.
	Chang HM, Yu HH, Yang YH, Lee WI, Lee JH, Wang LC, Lin YT, Chiang BL. Pediatr Infect Dis J. 2012;31(1):100-1.
	Vertebral osteomyelitis complicated by an epidural abscess from aspergillosis is rare.
20512571	MALE
	Invasive aspergillosis osteomyelitis in children--a case report and review of the literature.
	Winterstein AR, Bohndorf K, Vollert K, Wagner T, Gnekow A, Roemer FW. Skeletal Radiol. 2010;39(8):827-31.
	Invasive aspergillosis osteomyelitis in children--a case report and review of the literature.
17954195	MALE
	Aspergillus fumigatus-related spondylodiscitis in a heart transplant patient successfully treated with voriconazole.
	Weclawiak H, Garrouste C, Kamar N, Linas MD, Tall P, Dambrin C, Durand D, Rostaing L. Transplant Proc. 2007;39(8):2627-8.
	Of these, aspergillosis is usually associated with pneumopathy or facial sinusitis, and Aspergillus fumigatus is rarely responsible for osteomyelitis or spondylodiscitis.
17767099	MALE	Middle Aged
	Maxillary necrosis by mucormycosis. a case report and literature review.
	Auluck A. Med Oral Patol Oral Cir Bucal. 2007;12(5):E360-4.
	Maxillary necrosis can occur due to bacterial infections such as osteomyelitis, viral infections such as herpes zoster or fungal infections such as mucormycosis, aspergillosis etc.
14987203	MALE	Middle Aged
	Aspergillus vertebral osteomyelitis after simultaneous kidney-pancreas transplantation.
	Salvalaggio PR, Bassetti M, Lorber MI, Micheletto GC, Friedman AL, Andriole VT, Basadonna GP. Transpl Infect Dis. 2003;5(4):187-90.
	Aspergillus osteomyelitis is a rare complication of invasive aspergillosis after organ transplantation.
11722071	FEMALE	Middle Aged
	A novel technique for the reconstruction of infected full-thickness chest wall defects.
	Raffoul W, Dusmet M, Landry M, Ris HB. Ann Thorac Surg. 2001;72(5):1720-4.
	Three patients requiring large full-thickness resections of the anterolateral chest wall for chronic infections were treated accordingly, two presenting with chronic radionecrosis and osteomyelitis and one with chest wall invasion by pulmonary aspergillosis.
11100285	MALE
	Successful treatment of invasive aspergillosis in chronic granulomatous disease by granulocyte transfusions followed by peripheral blood stem cell transplantation.
	Bielorai B, Toren A, Wolach B, Mandel M, Golan H, Neumann Y, Kaplinisky C, Weintraub M, Keller N, Amariglio N, Paswell J, Rechavi G. Bone Marrow Transplant. 2000;26(9):1025-8.
	We report a 4-year-old boy with X-linked CGD who underwent successful HLA-identical peripheral blood stem cell (PBSC) transplantation during invasive pulmonary aspergillosis and osteomyelitis of the left fourth rib, which was unresponsive to antifungal treatment.
9154954	FEMALE	Adult
	Aspergillus osteomyelitis after heart-lung transplantation.
	Taillandier J, Alemanni M, Cerrina J, Le Roy Ladurie F, Dartevelle P. J Heart Lung Transplant. 1997;16(4):436-8.
	Aspergillus osteomyelitis is a severe complication of invasive aspergillosis.
8607085	FEMALE
	Aspergillosis of the sphenoid sinus: presentation as a pituitary mass and postoperative gallium-67 imaging.
	Parker KM, Nicholson JK, Cezayirli RC, Biggs PJ. Surg Neurol. 1996;45(4):354-8.
	We describe an elderly female patient with invasive aspergillosis of the sphenoid sinus and associated osteomyelitis of the skull base, with clinical presentation as a pituitary mass.
8369322	MALE	Middle Aged
	Aspergillosis with Aspergillus osteomyelitis and diskitis after heart transplantation: surgical and medical management.
	Hummel M, Schuler S, Weber U, Schwertlick G, Hempel S, Theiss D, Rees W, Mueller J, Hetzer R. J Heart Lung Transplant. 1993;12(4):599-603.
	This is the report of a 49-year-old man, who could be cured of aspergillosis with Aspergillus osteomyelitis and diskitis of the lumbar spine by medical and surgical therapy after heart retransplantation.
8369322	MALE	Middle Aged
	Aspergillosis with Aspergillus osteomyelitis and diskitis after heart transplantation: surgical and medical management.
	Hummel M, Schuler S, Weber U, Schwertlick G, Hempel S, Theiss D, Rees W, Mueller J, Hetzer R. J Heart Lung Transplant. 1993;12(4):599-603.
	Aspergillosis with Aspergillus osteomyelitis and diskitis after heart transplantation: surgical and medical management.
8369322	MALE	Middle Aged
	Aspergillosis with Aspergillus osteomyelitis and diskitis after heart transplantation: surgical and medical management.
	Hummel M, Schuler S, Weber U, Schwertlick G, Hempel S, Theiss D, Rees W, Mueller J, Hetzer R. J Heart Lung Transplant. 1993;12(4):599-603.
	Aspergillus osteomyelitis and diskitis is a rare complication of invasive aspergillosis.