Aspergillosis

A rare infectious disease caused by inhalation of the opportunistic fungus <i>aspergillus</i> that can lead to the following manifestations: allergic bronchopulmonary aspergillosis (ABPA), aspergilloma, chronic necrotizing pulmonary aspergillosis (CNPA), and invasive aspergillosis (IA). Aspergilloma occurs in patients with cavitary lung disease and results in a fungal mass with variable clinical presentations from asymptomatic to life-threatening (massive hemoptysis). CNPA manifests as subacute pneumonia in patients with underlying disease. IA is disseminated aspergillosis that eventually invades other organs. Cutaneous aspergillosis is usually the dermatological manifestation of IA that manifests as erythematous-to-violaceous plaques or papules, often characterized by a central necrotic ulcer or eschar.

Opportunistic fungal infection

An infection that is caused by a fungus that would generally not be able to cause an infection in a host with a normal immune system. Such fungi take advantage of the opportunity, so to speak, that is provided by a weakened immune system.


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(per page)
PMID (PMCID)
27251318
 MALE
A Case of Cutaneous Fusariosis of the Scrotum as a Complication of Acute Myeloid Leukemia.
Takenaka M.
Med Mycol J. 2016;57(2):J65-70.
During examination of necrotic lesions occurring on the skin of patients with hematological malignancies, it is important to include mycological examination for opportunistic fungal infections, such as aspergillosis or fusariosis, which are easily overlooked by routine culture methods using conventional media with cycloheximide.
26206431
 MALE
Isolated enteric aspergillosis in a non severely immunocompromised patient. Case report and literature review.
Koutsounas I, Pyleris E.
Arab J Gastroenterol. 2015;16(2):72-5.
Invasive aspergillosis is a life-threatening, opportunistic fungal infection that mainly affects immunocompromised patients, particularly those receiving immunosuppressive therapy or high-dose corticosteroids.
22965844
 MALE
Co-infection with invasive pulmonary aspergillosis and Pneumocystis jirovecii pneumonia after corticosteroid therapy.
Hagiya H, Miyake T, Kokumai Y, Murase T, Kuroe Y, Nojima H, Sugiyama J, Naito H, Hagioka S, Morimoto N.
J Infect Chemother. 2013;19(2):342-7.
Invasive pulmonary aspergillosis and P. jirovecii pneumonia are both life-threatening opportunistic fungal infections.
23248489
(3519232)
 OTHER
Chronic invasive aspergillosis of paranasal sinuses: A case report with review of literature.
Tamgadge AP, Mengi R, Tamgadge S, Bhalerao SS.
J Oral Maxillofac Pathol. 2012;16(3):460-4.
Aspergillosis of the nasal and paranasal sinuses is recognized as being second to candidiasis, among opportunistic fungal infections in immunocompromised patients.
22923910
(3424954)
 OTHER
Invasive aspergillosis in an immunocompetent host.
Sethi P, Saluja R, Jindal N, Singh V.
J Oral Maxillofac Pathol. 2012;16(2):297-300.
Aspergillosis is a common opportunistic fungal infection affecting the nose and paranasal sinuses.
21178487
 FEMALE Middle Aged
Successful, combined long-term treatment of cerebral aspergillosis in a liver transplant patient.
Tsitsopoulos PP, Tsoulfas G, Tsonidis C, Imvrios G, Papanikolaou V, Giakoustidis D, Marinopoulos D, Takoudas D, Tsitsopoulos PD.
Virulence. 2010;1(5):465-7.
Invasive aspergillosis has long been recognized as one of the most significant and often fatal opportunistic fungal infections in liver transplant recipients.
16429409
 MALE
Lethal double infection with Acremonium strictum and Aspergillus fumigatus during induction chemotherapy in a child with ALL.
Foell JL, Fischer M, Seibold M, Borneff-Lipp M, Wawer A, Horneff G, Burdach S.
Pediatr Blood Cancer. 2007;49(6):858-61.
Since there are only a few reports about invasive Acremonium infections, we present this case with regard to differences in the clinic pathologic features of Aspergillosis and other opportunistic fungal infections due to Fusarium or Acremonium species.
12063497
 FEMALE
Amphotericin B-resistant Aspergillus flavus infection successfully treated with caspofungin, a novel antifungal agent.
Koss T, Bagheri B, Zeana C, Romagnoli MF, Grossman ME.
J Am Acad Dermatol. 2002;46(6):945-7.
Invasive aspergillosis is uncommon in immunocompetent hosts but is the second most common opportunistic fungal infection in immunocompromised patients.