Feingold syndrome

Feingold syndrome (FS), also known as oculo-digito-esophageal-duodenal (ODED) syndrome, is a rare inherited malformation syndrome characterized by microcephaly, short stature and numerous digital anomalies and is comprised of two subtypes: FS type 1 (FS1) and FS type 2 (FS2) (see these terms). FS1 is by far the most common form while FS2 has only been reported in 3 patients and has the same clinical characteristics as FS1, apart from the absence of gastrointestinal atresia and short palpebral fissures.

Short palpebral fissure

Distance between the medial and lateral canthi is more than 2 SD below the mean for age (objective); or, apparently reduced length of the palpebral fissures.


Total: 3

                       


(per page)
PMID (PMCID)
19852433
 MALE Infant
A Feingold syndrome case with previously undescribed features and a new mutation.
Kocak H, Ozaydin E, Kose G, Marcelis CL, Kamsteeg EJ, Ceylaner S.
Genet Couns. 2009;20(3):261-7.
Feingold syndrome (FS) is a dominantly inherited combination of microcephaly with or without learning disabilities, hand and foot abnormalities, short palpebral fissures and esophageal/duodenal atresia.
10817649
 MIXED_SAMPLE Infant, Newborn
Imperforate anus in Feingold syndrome.
Buttiker V, Wojtulewicz J, Wilson M.
Am J Med Genet. 2000;92(3):166-9.
A father and daughter had the characteristic findings of Feingold syndrome including microcephaly, short palpebral fissures, brachydactyly with clinodactyly of fifth fingers, and bilateral syndactyly of second to third and fourth to fifth toes.
10911531
 MALE Infant
[Feingold syndrome].
Alessandri JL, Graber D, Tiran-Rajaofera I, Montbrun A, Pilorget H, Samperiz S, Attali T, de Napoli-Cocci S.
Arch Pediatr. 2000;7(6):637-40.
Feingold syndrome is a combination of hand and foot anomalies, microcephaly, tracheo-esophageal fistula, esophageal/duodenal atresia, short palpebral fissures and developmental delay.