Budd-Chiari syndrome

Budd-Chiari syndrome (BCS) is caused by obstruction of hepatic venous outflow involving either the hepatic veins or the terminal segment of the inferior vena cava.

Aphthous ulcer

Oral aphthous ulcers typically present as painful, sharply circumscribed fibrin-covered mucosal defects with a hyperemic border.


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PMID (PMCID)
20465622
 MALE Child
Severe aphthous stomatitis associated with oral calcineurin and mTOR inhibitors.
Habib N, Salaro C, Al-Ghaithi K, Phelps RG, Saggar S, Cohen SR.
Int J Dermatol. 2010;49(1):91-4.
We present an 11-year old male with Budd-Chiari syndrome who experienced profound worsening of chronic aphthous ulcers after immunosuppressive therapy was changed from tacrolimus to sirolimus.