Chronic beryllium disease

Chronic beryllium disease (CBD) is a granulomatous, interstitial lung disease that occurs in individuals who develop beryllium sensitization (BeS), a cell-mediated immune response to environmental and occupational beryllium exposure. BeS precedes the lung disease that may present with chronic dry cough, fatigue, weight loss, chest pain, and increasing dyspnea.

Pulmonary granulomatosis

The presence of multiple granulomata (small nodular inflammatory lesions containing grouped mononuclear phagocytes) in the lung.

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PMID (PMCID)
16716007	MALE	Adult
	Significant improvement from chronic beryllium disease following corticosteroid pulse therapy.
	Nagaoka K, Yoshida T, Sakakibara H, Kurita H, Taniwaki H, Ono Y. Ind Health. 2006;44(2):296-301.
	Chronic beryllium disease (CBD) is a rare disease characterized by diffuse interstitial pulmonary granulomatosis.