Macular amyloidosis

Macular amyloidosis (MA) is a rare chronic form of cutaneous amyloidosis (see this term), a skin disease characterized by the accumulation of amyloid deposits in the dermis, clinically characterized by pruritic hyperkeratotic gray-brown macules that give a rippled or reticulated pattern of pigmentation usually in the upper back and extensor sites of arms, forearms and legs, and histologically by the deposition of amyloid in the upper dermis and close to the basal cell layer of the epidermis. MA is commonly associated with other skin diseases, such as atopic dermatitis.

Poikiloderma

Poikiloderma refers to a patch of skin with (1) reticulated hypopigmentation and hyperpigmentation, (2) wrinkling secondary to epidermal atrophy, and (3) telangiectasias.


Total: 2

                      


(per page)
PMID (PMCID)
11194203
(3054712)
MALE Middle Aged
Macular amyloidosis presented as poikiloderma: a case report.
Kang HY, Kang WH.
J Korean Med Sci. 2000;15(6):724-6.
Macular amyloidosis presented as poikiloderma: a case report.
8776378
MALE
Macular amyloidosis with widespread diffuse pigmentation.
Wang CK, Lee JY.
Br J Dermatol. 1996;135(1):135-8.
We report two patients with an unusual variant of macular amyloidosis who had diffuse homogeneous hyperpigmentation without papules, a rippled pattern or poikiloderma.