Monosomy 18p

Monosomy 18p refers to a chromosomal disorder resulting from the deletion of all or part of the short arm of chromosome 18.

Chorea

Chorea (Greek for 'dance') refers to widespread arrhythmic involuntary movements of a forcible, jerky and restless fashion. It is a random-appearing sequence of one or more discrete involuntary movements or movement fragments. Movements appear random because of variability in timing, duration or location. Each movement may have a distinct start and end. However, movements may be strung together and thus may appear to flow randomly from one muscle group to another. Chorea can involve the trunk, neck, face, tongue, and extremities.


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(per page)
PMID (PMCID)
10073426
FEMALE
Progressive dystonia in a child with chromosome 18p deletion, treated with intrathecal baclofen.
Awaad Y, Munoz S, Nigro M.
J Child Neurol. 1999;14(2):75-7.
Neurologic findings in the 18p syndrome are reported to include mental retardation, seizures, incoordination, tremor, and chorea.