Castleman disease

Castleman disease (CD) is a benign lymphoproliferative disorder that may present as a localized or multicentric form (see these terms). The clinical manifestations are heterogeneous, ranging from asymptomatic discrete lymphadenopathy to recurrent episodes of diffuse lymphadenopathy with severe systemic symptoms.

Splenomegaly

Abnormal increased size of the spleen.


Total: 3

                       


(per page)
PMID (PMCID)
30906603
 OTHER
Castleman Disease in a Patient with Common Variable Immunodeficiency.
Ricciardi L, Furci F, Ieni A, Macri A.
Case Reports Immunol. 2019;2019:5476383.
Castleman disease (CD) is a systemic disease clinically characterized by diffuse lymphadenopathy, splenomegaly, anemia, and systemic inflammatory symptoms.
23094815
 MALE Middle Aged
[Our experience in treatment of multicentric plasma-cell Castleman disease associated with vasculitis manifestations - case report and literature review].
Szturz P, Adam Z, Moulis M, Smardova L, Klincova M, Slaisova R, Koukalova R, Rehak Z, Volfova P, Chovancova J, Stehlikova O, Mayer J.
Vnitr Lek. 2012;58(9):679-90.
The case report given here describes the 3-year experience with therapy in a patient, male born 1961, diagnosed with multicentric plasma-cell Castleman disease (HIV and HHV-8 negative) with the finding of generalized lymphadenopathy and splenomegaly.
21591454
 MALE Adult
[A case of pulmonary multicentric Castleman disease which appeared as a very large lesion].
Okamoto M, Hoshino T, Nakamura M, Imamura Y, Fujimoto K, Oshima K, Kawayama T, Aizawa H.
Nihon Kokyuki Gakkai Zasshi. 2011;49(4):266-70.
We made a diagnosis of multicentric Castleman disease based on high levels of serum IL-6, multiple lymph node enlargement and splenomegaly, although this case had histological findings in common not only with Castleman disease but also with inflammatory myofibroblastic tumor.