Castleman disease

Castleman disease (CD) is a benign lymphoproliferative disorder that may present as a localized or multicentric form (see these terms). The clinical manifestations are heterogeneous, ranging from asymptomatic discrete lymphadenopathy to recurrent episodes of diffuse lymphadenopathy with severe systemic symptoms.

Hypoalbuminemia

Reduction in the concentration of albumin in the blood.


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PMID (PMCID)
28501028
(5429940)
 FEMALE Adult
Multicentric Castleman disease of hyaline vascular variant presenting with unusual systemic manifestations: a case report.
Basnayake BMDB, Wazil AWM, Kannangara T, Ratnatunga NVI, Hewamana S, Ameer AM.
J Med Case Rep. 2017;11(1):135.
Investigations showed bicytopenia, nephrotic range proteinuria with hypoalbuminemia, hypogammaglobulinemia, and features of hyaline-vascular type Castleman disease in a lymph node biopsy.