Castleman disease

Castleman disease (CD) is a benign lymphoproliferative disorder that may present as a localized or multicentric form (see these terms). The clinical manifestations are heterogeneous, ranging from asymptomatic discrete lymphadenopathy to recurrent episodes of diffuse lymphadenopathy with severe systemic symptoms.

Low-grade fever

Mild fever that does not exceed 38.5 degree centrigrade.


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PMID (PMCID)
17665027
 MALE Adult
POEMS (polyneuropathy, organomegaly, endocrinopathy, M protein, skin lesions) syndrome: a South America's report.
Leite AC, Nascimento OJ, Lima MA, Andrada-Serpa MJ.
Arq Neuropsiquiatr. 2007;65(2B):516-20.
Several other associated conditions such as sclerotic bone lesions, Castleman disease, low-grade fever, edema and hematologic disorders are usually seen.