Dermatitis herpetiformis

A chronic autoimmune subepidermal bullous disease characterized by grouped pruritic lesions such as papules, urticarial plaques, erythema, and herpetiform vesiculae, with a predominantly symmetrical distribution on extensor surfaces of the elbows (90%), knees (30%), shoulders, buttocks, sacral region, and face of children and adults. Erosions, excoriations and hyperpigmentation usually follow. It may also appear as a consequence of gluten intolerance.

Autoimmunity

The occurrence of an immune reaction against the organism's own cells or tissues.


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PMID (PMCID)
20976416
MALE
Widespread vesiculobullous eruption in a 16-year-old male.
Piem J, Vizjak A, Tomi M, Luzar B.
Acta Dermatovenerol Alp Pannonica Adriat. 2010;19(3):19-22.
BSLE is characterized by a dermatitis herpetiformis-like histology and an autoimmunity to type VII collagen.