Dermatitis herpetiformis

A chronic autoimmune subepidermal bullous disease characterized by grouped pruritic lesions such as papules, urticarial plaques, erythema, and herpetiform vesiculae, with a predominantly symmetrical distribution on extensor surfaces of the elbows (90%), knees (30%), shoulders, buttocks, sacral region, and face of children and adults. Erosions, excoriations and hyperpigmentation usually follow. It may also appear as a consequence of gluten intolerance.

Papule

A circumscribed, solid elevation of skin with no visible fluid, varying in size from a pinhead to less than 10mm in diameter at the widest point.

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PMID (PMCID)
23970137	MALE	Adult
	Acral purpura as leading clinical manifestation of dermatitis herpetiformis: report of two adult cases with a review of the literature.
	Tu H, Parmentier L, Stieger M, Spanou Z, Horn M, Beltraminelli H, Borradori L. Dermatology. 2013;227(1):1-4.
	Dermatitis herpetiformis (DH) is an autoimmune disease that clinically manifests as pruritic vesicles and papules.
7008639	MALE	Middle Aged
	Hodgkin's disease with specific bullous lesions.
	Hanno R, Bean SF. Am J Dermatopathol. 1980;2(4):363-6.
	A variety of bullous eruptions have been reported in patients with Hodgkin's disease, among them erythema multiforme, herpesvirus infections, bullous impetigo, prurigo-like papules with vesicles, drug eruptions, bullous pemphigoid, dermatitis herpetiformis, and acquired epidermolysis bullosa.