Diencephalic syndrome

Diencephalic syndrome (DS) is a rare condition characterized by profound emaciation and failure to thrive (with normal caloric intake and normal linear growth), hyperalertness, hyperkinesia and euphoria, in the presence of hypothalamic tumors.

Hydrocephalus

Hydrocephalus is an active distension of the ventricular system of the brain resulting from inadequate passage of CSF from its point of production within the cerebral ventricles to its point of absorption into the systemic circulation.


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(per page)
PMID (PMCID)
6739045
FEMALE Infant
Acquired nystagmus in early childhood: a presenting sign of intracranial tumor.
Lavery MA, O'Neill JF, Chu FC, Martyn LJ.
Ophthalmology. 1984;91(5):425-53.
Three associated clinical findings were present or developed in these patients to distinguish this entity from spasmus nutans : optic atrophy in all ten patients, poor feeding due to diencephalic syndrome in 5 of 10, and increased intracranial pressure with hydrocephalus in 3 of 10.