Diencephalic syndrome

Diencephalic syndrome (DS) is a rare condition characterized by profound emaciation and failure to thrive (with normal caloric intake and normal linear growth), hyperalertness, hyperkinesia and euphoria, in the presence of hypothalamic tumors.

Increased intracranial pressure

An increase of the pressure inside the cranium (skull) and thereby in the brain tissue and cerebrospinal fluid.


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PMID (PMCID)
6739045
 FEMALE Infant
Acquired nystagmus in early childhood: a presenting sign of intracranial tumor.
Lavery MA, O'Neill JF, Chu FC, Martyn LJ.
Ophthalmology. 1984;91(5):425-53.
Three associated clinical findings were present or developed in these patients to distinguish this entity from spasmus nutans : optic atrophy in all ten patients, poor feeding due to diencephalic syndrome in 5 of 10, and increased intracranial pressure with hydrocephalus in 3 of 10.