Autosomal dominant spastic paraplegia type 37

A pure form of hereditary spastic paraplegia characterized by a childhood- to adulthood-onset of slowly progressive spastic gait, extensor plantar responses, brisk tendon reflexes in arms and legs, decreased vibration sense at ankles and urinary dysfunction. Ankle clonus is also reported in some patients.

Urinary urgency

Urge incontinence is the strong, sudden need to urinate.


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