Paget disease of the nipple

Paget disease of the nipple describes a rare presentation of breast cancer, seen most frequently in women aged 50-60, manifesting with nipple drainage and itching, erythema, crusty and excoriated nipple, thickened plaques, and hyperpigmentation (less frequently). It is due to tumor cells invading the nipple-areola complex and represents 1-3% of all new breast cancer diagnoses.

Papilloma

A tumor of the skin or mucous membrane with finger-like projections.

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PMID (PMCID)
10578697	FEMALE	Middle Aged
	[Adenoma of the nipples. A rare, but essential differential diagnosis].
	Barsi T, Hoyer S, Mortensen J. Ugeskr Laeger. 1999;161(42):5807-8.
	Adenoma of the nipple is a rare, but benign condition, which clinically can be confused with Paget's disease of the nipple, intraductal papilloma and adenocarcinoma of the breast.