Evans syndrome

A rare chronic hematologic disorder characterized by the simultaneous or sequential association of autoimmune hemolytic anemia (AIHA; a disorder in which auto-antibodies are directed against red blood cells causing anemia of varying degrees of severity) with immune thrombocytopenic purpura (ITP; a coagulation disorder in which auto-antibodies are directed against platelets causing hemorrhagic episodes) and occasionally autoimmune neutropenia, in the absence of a known underlying etiology.

Autoimmunity

The occurrence of an immune reaction against the organism's own cells or tissues.

Total: 2

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PMID (PMCID)
26150183	FEMALE	Adult
	A Case of a TSH-secreting Pituitary Adenoma Associated with Evans' Syndrome.
	Yasuda A, Seki T, Oki M, Takagi A, Inomoto C, Nakamura N, Atsumi H, Baba T, Matsumae M, Sasaki N, Suzuki Y, Fukagawa M. Tokai J Exp Clin Med. 2015;40(2):44-50.
	Our report suggests that the excess of thyroid hormone itself promotes autoimmunity in Evans' syndrome.
23590417	MIXED_SAMPLE	Child
	Variable presentation of primary immune deficiency: two cases with CD3 gamma deficiency presenting with only autoimmunity.
	Tokgoz H, Caliskan U, Keles S, Reisli I, Guiu IS, Morgan NV. Pediatr Allergy Immunol. 2013;24(3):257-62.
	Here, we present two siblings from non-consanguineous family with autoimmunity including Evans syndrome, autoimmune hepatitis, nephrotic syndrome, and Hashimoto's thyroiditis and with no previous history of infections.