Evans syndrome

A rare chronic hematologic disorder characterized by the simultaneous or sequential association of autoimmune hemolytic anemia (AIHA; a disorder in which auto-antibodies are directed against red blood cells causing anemia of varying degrees of severity) with immune thrombocytopenic purpura (ITP; a coagulation disorder in which auto-antibodies are directed against platelets causing hemorrhagic episodes) and occasionally autoimmune neutropenia, in the absence of a known underlying etiology.

Thyroiditis

Inflammation of the thyroid gland.


Total: 7

                       


(per page)
PMID (PMCID)
23961497
(3743381)
 OTHER
Hashimoto's thyroiditis associated Evans syndrome: A rare case report on the clustered autoimmune disease triad.
Koti K, Thumma RR, Nagarajan S, Mathi A.
Indian J Endocrinol Metab. 2013;17(4):736-9.
Their association with autoimmune thyroid diseases has been reported by few authors; however, a sequential development of the Evans syndrome in cases of Hashimoto's thyroiditis is extremely rare.
23590417
 MIXED_SAMPLE Child
Variable presentation of primary immune deficiency: two cases with CD3 gamma deficiency presenting with only autoimmunity.
Tokgoz H, Caliskan U, Keles S, Reisli I, Guiu IS, Morgan NV.
Pediatr Allergy Immunol. 2013;24(3):257-62.
Here, we present two siblings from non-consanguineous family with autoimmunity including Evans syndrome, autoimmune hepatitis, nephrotic syndrome, and Hashimoto's thyroiditis and with no previous history of infections.
22259635
(3259521)
 OTHER
Evans syndrome following long-standing Hashimoto's thyroiditis and successful treatment with rituximab.
Oh HJ, Yun MJ, Lee ST, Lee SJ, Oh SY, Sohn I.
Korean J Hematol. 2011;46(4):279-82.
Evans syndrome and autoimmune thyroiditis might share common pathophysiological mechanisms.
21397466
 MIXED_SAMPLE Child
[Hodgkin disease and autoimmunity in children: 11 case reports].
Jarrasse C, Pagnier A, Edan C, Landman-Parker J, Mazingue F, Mansuy L, Bertrand Y, Paillard C, Pellier I, Margueritte G, Plantaz D.
Arch Pediatr. 2011;18(4):376-82.
Four patients had thrombocytopenic purpura, the remaining 7 each had a different autoimmune pathology: lupus syndrome, antiphospholipid syndrome with transient ischemic attack, Evans syndrome, leukocytoclastic vasculitis, autoimmune hemolytic anemia, autoimmune thyroiditis, and juvenile idiopathic arthritis.
16807996
(2688166)
 FEMALE Adult
A 20-year-old woman with Hashimoto's thyroiditis and Evans' syndrome.
Kang MY, Hahm JR, Jung TS, Lee GW, Kim DR, Park MH.
Yonsei Med J. 2006;47(3):432-6.
Hashimoto's thyroiditis is often associated with other nonendocrine autoimmune diseases, and antithyroid antibodies are frequently observed in Evans' syndrome (coexistence of AIHA and ITP).
16807996
(2688166)
 FEMALE Adult
A 20-year-old woman with Hashimoto's thyroiditis and Evans' syndrome.
Kang MY, Hahm JR, Jung TS, Lee GW, Kim DR, Park MH.
Yonsei Med J. 2006;47(3):432-6.
A 20-year-old woman with Hashimoto's thyroiditis and Evans' syndrome.
16807996
(2688166)
 FEMALE Adult
A 20-year-old woman with Hashimoto's thyroiditis and Evans' syndrome.
Kang MY, Hahm JR, Jung TS, Lee GW, Kim DR, Park MH.
Yonsei Med J. 2006;47(3):432-6.
However, there is no report of Evans' syndrome developing in patients with overt hypothyroidism and Hashimoto's thyroiditis.