Cornelia de Lange syndrome

Cornelia de Lange syndrome (CdLS) is a multisystem disorder with variable expression marked by a characteristic facial dysmorphism, variable degrees of intellectual deficit, severe growth retardation beginning before birth (2nd trimester), abnormal hands and feet (oligodactyly, or sometimes an even more severe amputation, and constant brachymetacarpia of the first metacarpus), and various other malformations (heart, kidney <i>etc.</i>).

Anemia

A reduction in erythrocytes volume or hemoglobin concentration.

Total: 1

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PMID (PMCID)
3772265	FEMALE	Middle Aged
	The hand-foot-uterus syndrome: a case study.
	Longmuir GA, Conley RN, Nicholson DL, Whitehead M. J Manipulative Physiol Ther. 1986;9(3):213-7.
	Distal extremity malformations are characteristic and superficially resemble those of arthrogryposis, chondroectodermal dysplasia, Cornelia de Lange syndrome, Faconi's anemia or Holt-Oram syndrome.