Harlequin syndrome

Harlequin syndrome (HSD) is an autonomic disorder occurring at any age and characterized by unilateral flushing and sweating, involving the face and sometimes arm and chest, in condition of thermal, exercise or emotional stress without sympathetic ocular manifestations. However, tonic pupils, parasympathetic oculomotor lesion and pre- or postganglionic sudomotor sympathetic deficit can rarely occur.

Miosis

Abnormal (non-physiological) constriction of the pupil.

Total: 2

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PMID (PMCID)
28291413	FEMALE	Middle Aged
	Harlequin sign concomitant with Horner syndrome after anterior cervical discectomy: a case of intrusion into the cervical sympathetic system.
	Fringeli Y, Humm AM, Ansorge A, Maestretti G. J Neurosurg Spine. 2017;26(6):684-687.
	Like Horner syndrome, associating miosis, ptosis, and anhidrosis, Harlequin syndrome is caused by disruption of the cervical sympathetic pathways.
8250530	MIXED_SAMPLE	Adult
	Site of autonomic deficit in harlequin syndrome: local autonomic failure affecting the arm and the face.
	Drummond PD, Lance JW. Ann Neurol. 1993;34(6):814-9.
	The site of autonomic deficit was investigated in 4 patients with loss of thermoregulatory flushing and sweating on one side of the face but no associated miosis (harlequin syndrome).