Lymphatic filariasis

Lymphatic filariasis (LF) is a severe form of filariasis (see this term), caused by the parasitic worms <i>Wuchereria bancrofti</i>, <i>Brugia malayi</i> and <i>Brugia timori</i>, and the most common cause of acquired lymphedema worldwide. LF is endemic to tropical and subtropical regions. The vast majority of infected patients are asymptomatic but it can also cause a variety of clinical manifestations, including limb lymphedema, genital anomalies (hydrocele, chylocele), elephantiasis in later stages of the disease (frequently in the lower extremities), and tropical pulmonary eosinophilia (nocturnal paroxysmal cough and wheezing, weight loss, low-grade fever, adenopathy, and pronounced blood eosinophilia). Renal involvement (hematuria, proteinuria, nephritic syndrome, glomerulonephritis), and mono-arthritis of the knee or ankle joint have also been reported.

Eosinophilia

Increased count of eosinophils in the blood.


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PMID (PMCID)
28944146
 OTHER
Filarial huge splenomegaly dramatically regressed by anti-filarial medication: A rare clinical scenario.
Basu A, Kumar A, Manchanda S, Wig N.
Intractable Rare Dis Res. 2017;6(3):215-218.
Lymphatic filariasis is a spectrum of illness and can manifest as, asymptomatic microfilaraemia, acute lymphatic filariasis (lymphangitis and lymphoedema), chronic lymphoedema, elephantiasis, hydrocele, tropical pulmonary eosinophilia and some systemic manifestations which involves joint, heart, kidney, nerve, etc.
28944146
 OTHER
Filarial huge splenomegaly dramatically regressed by anti-filarial medication: A rare clinical scenario.
Basu A, Kumar A, Manchanda S, Wig N.
Intractable Rare Dis Res. 2017;6(3):215-218.
Lymphatic filariasis is a spectrum of illness and can manifest as, asymptomatic microfilaraemia, acute lymphatic filariasis (lymphangitis and lymphoedema), chronic lymphoedema, elephantiasis, hydrocele, tropical pulmonary eosinophilia and some systemic manifestations which involves joint, heart, kidney, nerve, etc.
705299
 MIXED_SAMPLE Child
[Clinical aspects, diagnosis and therapy of tropical pulmonary eosinophilia].
Sturchler D, Imbach P, Gartmann J, Degremont A.
Schweiz Med Wochenschr. 1978;108(38):1461-4.
In Switzerland, tropical pulmonary eosinophilia occurs in subjects who have stayed in endemic areas of lymphatic filariasis (mainly India and South East Asia) and in adopted children from these countries.