Immune-mediated necrotizing myopathy

Necrotizing autoimmune myopathy (NAM) is a rare form of idiopathic inflammatory myopathy characterized clinically by acute or subacute proximal muscle weakness, and histopathologically by myocyte necrosis and regeneration without significant inflammation.

Edema

An abnormal accumulation of fluid beneath the skin, or in one or more cavities of the body.


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(per page)
PMID (PMCID)
25883715
(4394925)
OTHER
Immune-mediated necrotizing myopathy, associated with antibodies to signal recognition particle, together with lupus nephritis: case presentation and management.
O'Grady J, Harty L, Mayer N, Critcher V, Ryan J.
J Clin Med Res. 2015;7(6):490-4.
A male patient with limb weakness, myalgia and edema was subsequently found to have an immune-mediated necrotizing myopathy (IMNM) on biopsy.