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Immune-mediated necrotizing myopathy

Necrotizing autoimmune myopathy (NAM) is a rare form of idiopathic inflammatory myopathy characterized clinically by acute or subacute proximal muscle weakness, and histopathologically by myocyte necrosis and regeneration without significant inflammation.

Proximal muscle weakness

A lack of strength of the proximal muscles.

Total: 1

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PMID (PMCID)
30788073	OTHER
	Anti-HMG-CoA reductase myopathy, an undesirable evolution of statin induced myopathy: a case report.
	Upreti S, Fayyaz B, Bongu RP. J Community Hosp Intern Med Perspect. 2019;9(1):33-35.
	However, an entity called Immune Mediated Necrotizing Myopathy (IMNM), a type of autoimmune mediated myopathy, has been recognized and characterized in patients with history of statin exposure where there is persistence of proximal muscle weakness, CK elevation and myofiber necrosis can be seen on muscle biopsy even after stopping statins.