Hydranencephaly

A rare cerebral malformation characterized by an almost or complete lack of cortex, specifically the cerebral hemispheres, with the cranium and meninges completely intact. In most cases, death occurs in utero or in the first weeks of life. Developmental delay, drug-resistant seizures, spastic diplegia, severe growth failure, deafness and blindness are typical.

Median cleft lip

A type of cleft lip presenting as a midline (median) gap in the upper lip.


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PMID (PMCID)
3078619
 FEMALE Child
A rare patient with a false median cleft lip associated with multiple congenital anomalies.
Ohtsuka H.
Ann Plast Surg. 1986;17(2):155-60.
A girl manifesting a false median cleft lip associated with hypertelorism, anophthalmos, hydranencephaly with holoprosencephaly, and osteogenesis imperfecta, among other disorders, survived and was fed mainly milk products up to the age of 11.