Dermatomyositis

A type of idiopathic inflammatory myopathy characterized by evocative skin lesions and symmetrical proximal muscle weakness.

Elevated serum creatine kinase

An elevation of the level of the enzyme creatine kinase (also known as creatine phosphokinase, CPK; EC 2.7.3.2) in the blood. CPK levels can be elevated in a number of clinical disorders such as myocardial infarction, rhabdomyolysis, and muscular dystrophy.


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PMID (PMCID)
22790579
 FEMALE Middle Aged
[Case of immunosuppressant-resistant amyopathic dermatomyositis with rapidly progressive interstitial pneumonia ameliorated after resection of gastric cancer].
Nogi S, Hashimoto A, Iwata K, Futami H, Takaoka H, Arinuma Y, Shimada K, Nakayama H, Matsui T, Komiya A, Furukawa H, Tamama S, Kinoshita S, Moriya H, Tohma S.
Nihon Rinsho Meneki Gakkai Kaishi. 2012;35(3):188-93.
At first presentation she showed cutaneous manifestations including heliotrope eyelids and mechanic's hands, slightly elevated serum creatine kinase (CK), elevated serum C-reactive protein level, and interstitial pneumonia (IP), which led to a diagnosis as dermatomyositis.