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Aortic arch interruption

A rare heart defect characterized by complete lack of anatomical continuity between the transverse aortic arch and the descending thoracic aorta. AAI should be distinguished anatomically from atresia of the aortic arch where continuity between these segments is achieved by an imperforate fibrous strand of various lengths.

Interrupted aortic arch

Non-continuity of the arch of aorta with an atretic point or absent segment.

Total: 1

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PMID (PMCID)
12503105	MIXED_SAMPLE	Infant, Newborn
	Interrupted aortic arch in a child with trisomy 5q31.1q35.1 due to a maternal (20;5) balanced insertion.
	Martin DM, Mindell MH, Kwierant CA, Glover TW, Gorski JL. Am J Med Genet A. 2003;116A(3):268-71.
	Chromosomal deletions, including deletion 22q11, have been reported with interrupted aortic arch (IAA); however, to our knowledge this is the first report of a trisomy of distal chromosome 5q associated with aortic arch interruption.