Sickle cell anemia

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Renal insufficiency

A reduction in the level of performance of the kidneys in areas of function comprising the concentration of urine, removal of wastes, the maintenance of electrolyte balance, homeostasis of blood pressure, and calcium metabolism.

Total: 3

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PMID (PMCID)
15111378	MIXED_SAMPLE	Adult
	Renal tubular acidosis, Sjogren syndrome, and bone disease.
	Fulop M, Mackay M. Arch Intern Med. 2004;164(8):905-9.
	Further detailed survey was then limited to patients older than 15 years and excluded those with potentially confounding causes of bone disease such as chronic renal insufficiency or sickle cell disease.
8197046	MALE	Adult
	Central nervous system toxicity associated with meperidine use in hepatic disease.
	Danziger LH, Martin SJ, Blum RA. Pharmacotherapy. 1994;14(2):235-8.
	Normeperidine is eliminated by the kidneys and accumulates in patients with renal insufficiency, sickle cell disease, and cancer.
6540413	MALE	Adult
	Interpretation of serum phenytoin concentrations in uremia is assay-dependent.
	Sirgo MA, Green PJ, Rocci ML Jr, Vlasses PH. Neurology. 1984;34(9):1250-1.
	A 25-year-old man with sickle cell disease and chronic renal insufficiency had tonic-clonic seizures treated with phenytoin.