Sickle cell anemia

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Rheumatoid arthritis

Inflammatory changes in the synovial membranes and articular structures with widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, as well as atrophy and rarefaction of bony structures.


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PMID (PMCID)
18200471
 FEMALE Middle Aged
Mitral valve replacement and tricuspid valve repair in a patient with sickle cell disease.
Lazopoulos G, Kantartzis MM, Kantartzis M.
Thorac Cardiovasc Surg. 2008;56(1):56-7.
We report the management of a 57-year-old Greek woman with homozygous sickle cell disease and rheumatoid arthritis, who underwent preoperative partial exchange transfusion and subsequent mitral valve replacement and tricuspid valve repair at normothermia.
16076916
 FEMALE Middle Aged
Glycemic monitoring in diabetics with sickle cell plus beta-thalassemia hemoglobinopathy.
Kosecki SM, Rodgers PT, Adams MB.
Ann Pharmacother. 2005;39(9):1557-60.
A 53-year-old African American woman presented with a past medical history of type 2 diabetes, hypertension, seizure disorder, rheumatoid arthritis, and sickle cell disease plus beta-thalassemia.
9364836
 MALE
Anemia secondary to low erythropoietin in a patient with normal renal function.
Kallab AM, Dabaghian G, Terjanian T.
Mt Sinai J Med. 1997;64(6):406-8.
Anemia with a relatively low erythropoietin level has been described in several medical conditions associated with chronic inflammatory diseases such as rheumatoid arthritis, cancer, sickle cell disease, chronic renal failure, acquired immunodeficiency syndrome, and severe autonomic nervous system failure.
2213765
 MALE Middle Aged
Rheumatoid arthritis in a patient with sickle cell disease.
Marino C, McDonald E.
J Rheumatol. 1990;17(7):970-2.
Coexistent rheumatoid arthritis (RA) and sickle cell disease has been reported rarely.
3663256
 FEMALE Adult
Sickle cell crisis following intraarticular steroid therapy for rheumatoid arthritis.
Gladman DD, Bombardier C.
Arthritis Rheum. 1987;30(9):1065-8.
We describe 2 patients who had coexistent rheumatoid arthritis and sickle cell disease.