Sickle cell anemia

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Cirrhosis

A chronic disorder of the liver in which liver tissue becomes scarred and is partially replaced by regenerative nodules and fibrotic tissue resulting in loss of liver function.

Total: 12

(per page)

PMID (PMCID)
28696845	MIXED_SAMPLE	Adult
	Decompensated Cirrhosis and Sickle Cell Disease: Case Reports and Review of the Literature.
	D'Ambrosio R, Maggioni M, Donato MF, Lampertico P, Cappellini MD, Graziadei G. Hemoglobin. 2017;41(2):131-133.
	Few data have been provided on chronic sickle cell intrahepatic cholestasis (SCIC) clinical course, although cirrhosis has been reported in sickle cell disease.
28696845	MIXED_SAMPLE	Adult
	Decompensated Cirrhosis and Sickle Cell Disease: Case Reports and Review of the Literature.
	D'Ambrosio R, Maggioni M, Donato MF, Lampertico P, Cappellini MD, Graziadei G. Hemoglobin. 2017;41(2):131-133.
	Decompensated Cirrhosis and Sickle Cell Disease: Case Reports and Review of the Literature.
28696845	MIXED_SAMPLE	Adult
	Decompensated Cirrhosis and Sickle Cell Disease: Case Reports and Review of the Literature.
	D'Ambrosio R, Maggioni M, Donato MF, Lampertico P, Cappellini MD, Graziadei G. Hemoglobin. 2017;41(2):131-133.
	Here we present two cases of adult sickle cell disease patients with decompensated cirrhosis.
28330494 (5362990)	FEMALE	Infant
	Pseudomonas oryzihabitans sepsis in a 1-year-old child with multiple skin rashes: a case report.
	Owusu M, Owusu-Dabo E, Acheampong G, Osei I, Amuasi J, Sarpong N, Annan A, Chiang HY, Kuo CH, Park SE, Marks F, Adu-Sarkodie Y. J Med Case Rep. 2017;11(1):77.
	The bacterium has been isolated in a few reported cases of neurosurgical infections and patients with end-stage cirrhosis, sickle cell disease, and community-acquired urinary tract infections.
25859482	OTHER
	Cirrhosis: an unusual presentation of sickle cell disease.
	Dosi R, Patell R, Jariwala P, Shah P, Jasdanwala S. J Clin Diagn Res. 2015;9(2):OD03-4.
	Cirrhosis: an unusual presentation of sickle cell disease.
21103241 (2988917)	OTHER
	Liver Cirrhosis in a Patient with Sickle Cell Trait (Hb Sbeta Thalassemia) without Other Known Causes of Hepatic Disease.
	Santi L, Montanari G, Berardi S, Patti C, Frigerio M, Sama C, Caraceni P, Bernardi M. Case Rep Gastroenterol. 2009;3(3):275-279.
	Thus, cirrhosis has been described almost exclusively in patients with sickle cell anemia, while only mild liver abnormalities have been associated with the sickle cell trait.
21103241 (2988917)	OTHER
	Liver Cirrhosis in a Patient with Sickle Cell Trait (Hb Sbeta Thalassemia) without Other Known Causes of Hepatic Disease.
	Santi L, Montanari G, Berardi S, Patti C, Frigerio M, Sama C, Caraceni P, Bernardi M. Case Rep Gastroenterol. 2009;3(3):275-279.
	Approximately 15-30% of patients with sickle cell anemia present cirrhosis at autopsy.
21103241 (2988917)	OTHER
	Liver Cirrhosis in a Patient with Sickle Cell Trait (Hb Sbeta Thalassemia) without Other Known Causes of Hepatic Disease.
	Santi L, Montanari G, Berardi S, Patti C, Frigerio M, Sama C, Caraceni P, Bernardi M. Case Rep Gastroenterol. 2009;3(3):275-279.
	Liver involvement in patients with sickle cell anemia/trait includes a wide range of alterations, from mild liver function test abnormalities to cirrhosis and acute liver failure.
17171533	MALE	Middle Aged
	Exacerbation of sickle cell disease itself as a cause of abnormal liver chemistry tests.
	Stanca CM, Fiel MI, Schiano TD. Dig Dis Sci. 2007;52(1):176-8.
	Liver pathology occurring in patients with sickle cell disease is commonly related to viral hepatitis or hepatic iron deposition due to repeated transfusions; cholestasis and cirrhosis may also occur.
8962593	MALE	Infant
	Acute neurotoxicity of meperidine in an infant.
	Saneto RP, Fitch JA, Cohen BH. Pediatr Neurol. 1996;14(4):339-41.
	What distinguished our patient from those previously reported was his minimal exposure to therapeutic doses of meperidine in the setting of normal renal function, and no history of sickle cell anemia, cancer, hepatitis, or cirrhosis.
7570991	FEMALE	Middle Aged
	Liver transplantation in a patient with sickle cell anemia.
	Kindscher JD, Laurin J, Delcore R, Forster J. Transplantation. 1995;60(7):762-4.
	We describe the case of a 47-year-old patient with sickle cell disease and hepatitis C virus-induced cirrhosis who required liver transplantation.
6698374	FEMALE	Adult
	Hepatic biloma complicating sickle cell disease. A case report and a review of the literature.
	Middleton JP, Wolper JC. Gastroenterology. 1984;86(4):743-4.
	Previously reported hepatobiliary complications of sickle cell disease include cholelithiasis, intrahepatic cholestasis, cirrhosis, hepatic crisis, abscess, and infarction.