Sickle cell anemia

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Hepatosplenomegaly

Simultaneous enlargement of the liver and spleen.


Total: 2

                       


(per page)
PMID (PMCID)
15495257
 MALE Adult
Sickle cell crisis associated with hemophagocytic lymphohistiocytosis.
Kio E, Onitilo A, Lazarchick J, Hanna M, Brunson C, Chaudhary U.
Am J Hematol. 2004;77(3):229-32.
We present a case of an African American male who was first diagnosed with sickle cell disease (SCD) at the age 23 years when he presented with generalized bone pain, fever, and hepatosplenomegaly.
6886145
 MIXED_SAMPLE Infant
Malignant histiocytosis in a patient with sickle cell anemia: CT findings.
Wong WS, Sherman NE, Moss AA.
J Comput Assist Tomogr. 1983;7(5):908-10.
The purpose of this report is to describe the serial CT findings of an unusual case of malignant histiocytosis in a patient with sickle cell anemia, presenting with weight loss and hepatosplenomegaly.