Sickle cell anemia

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Cardiomegaly

Increased size of the heart.


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PMID (PMCID)
615614
 MIXED_SAMPLE Infant
[Hemoglobinpathy S--clinical manifestations in children in a Zairian family].
Curcic B, Popovic M, Cahurska T, Beksedic D.
Bilt Hematol Transfuz. 1977;5(3-4):81-7.
The Youngest child, girl two years of age, is homozygous with complete Sickle cell disease: hand-foot syndrome, heterotopic paravertebral hematopoetic tissue, lung infarctions, cardiomegaly, severe drepanocytic anaemia; she succumbed in an a attack after many episodes of severe hypoxia.