Sickle cell anemia

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Neutropenia

An abnormally low number of neutrophils in the peripheral blood.


Total: 1

                      


(per page)
PMID (PMCID)
22758217
MALE
Coexistence of sickle cell disease and severe congenital neutropenia: first impressions can be deceiving.
Wali Y, Beshlawi I, Fawaz N, Alkhayat A, Zalabany M, Elshinawy M, Al-Kindi S, Al-Rawas AH, Klein C.
Eur J Haematol. 2012;89(3):245-9.
These clinical observations suggest that neutropenia may ameliorate inflammatory responses and thus display a modulating factor with respect to the clinical course of sickle cell disease.