Sickle cell anemia

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Hemolytic anemia

A type of anemia caused by premature destruction of red blood cells (hemolysis).


Total: 11

                       


(per page)
PMID (PMCID)
28766838
 MIXED_SAMPLE Child
Transfusion-transmitted babesiosis leading to severe hemolysis in two patients with sickle cell anemia.
Karkoska K, Louie J, Appiah-Kubi AO, Wolfe L, Rubin L, Rajan S, Aygun B.
Pediatr Blood Cancer. 2018;65(1):.
The intracellular parasites Babesia microti and Babesia duncani can be transmitted by blood transfusion and cause severe life-threatening hemolytic anemia in high-risk patients, including those with sickle cell disease.
25960732
(4410510)
 OTHER
Irreversible Loss of Vision in a Child due to Occipital Infarction after Gastroenteritis.
Mansour AM, Hasbini D, Younis MH, Bhatti MT.
Case Rep Ophthalmol. 2015;6(1):106-9.
Evaluations for sickle cell anemia, hemolytic anemia and coagulopathies were negative.
25163809
 MALE Child
Ceftriaxone-induced immune hemolytic anemia.
Neuman G, Boodhan S, Wurman I, Koren G, Bitnun A, Kirby-Allen M, Ito S.
Ann Pharmacother. 2014;48(12):1594-604.
To describe a case of ceftriaxone-induced immune hemolytic anemia (CIIHA) in a 6 year-old boy with sickle cell disease (SCD) and perform a systematic literature review to delineate the clinical and laboratory features of this condition.
22430586
 MALE
Pseudotumor cerebri in a Turkish boy with Fanconi anemia.
Tavil B, Karakurt N, Bozkaya I, Culha V, Mehmet Azk F, Tunc B.
J Pediatr Hematol Oncol. 2012;34(4):296-7.
Although PC is described in patients with various hematological diseases including iron-deficiency anemia, megaloblastic anemia, acquired aplastic anemia, hemolytic anemia, sickle cell disease, and paroxysmal nocturnal hemoglobinuria, there is no case of PC with Fanconi anemia in the English literature.
19066384
(2756016)
 FEMALE Adult
Evolution of novel small-molecule therapeutics targeting sickle cell vasculopathy.
Kato GJ, Gladwin MT.
JAMA. 2008;300(22):2638-46.
Recent research has suggested a syndrome of hemolysis-associated vasculopathy in patients with sickle cell disease, which features severe hemolytic anemia and leads to scavenging of nitric oxide and its biochemical precursor l-arginine.
18363174
 FEMALE Infant
Pulmonary hypertension in children with Evans syndrome.
Connor P, Veys P, Amrolia P, Haworth S, Ashworth M, Moledina S.
Pediatr Hematol Oncol. 2008;25(2):93-8.
The authors speculate that the pulmonary hypertension was caused by the underlying immune dysregulation and hemolysis and that Evans syndrome joins the list of other hemolytic anemias that cause pulmonary hypertension, such as sickle cell disease, thalassemia, and paroxysmal nocturnal hemoglobinuria.
17356397
 MALE Adult
Pulmonary hypertension in a case of Hb-Mainz hemolytic anemia.
Lode HN, Krings G, Schulze-Neick I, Dahmlow S, Schroeder U, Bonnet R, DaPalma J, Luck W, Strauss G, Berger F, Gaedicke G.
J Pediatr Hematol Oncol. 2007;29(3):173-7.
The development of pulmonary arterial hypertension (PAH) is the leading cause of mortality in patients with thalassemia and sickle cell anemia and was reported to occur in hemolytic anemias such as hereditary stomatocytosis, and paroxysmal nocturnal hemoglobinuria.
9308316
 MALE Adult
Aplastic crisis associated with parvovirus B19 in an adult with hereditary spherocytosis.
Beland SS, Daniel GK, Menard JC, Miller NM.
J Ark Med Soc. 1997;94(4):163-4.
The association between acute red blood cell aplasia and infection with parvovirus B19 is well described in patients with hereditary hemolytic anemia, particularly sickle cell anemia.
2727649
 MALE Child
Sickle cell anemia and mitral valve replacement. Case report.
Bomfim V, Ribeiro A, Gouvea F, Pereira J, Bjork V.
Scand J Thorac Cardiovasc Surg. 1989;23(1):75-7.
An 8-year-old black boy with sickle cell disease and severe hemolytic anemia crisis (95% hemoglobin S) also had mitral incompetence due to rheumatic valve disease.
3021015
 MALE
Human parvovirus-associated red cell aplasia in the absence of underlying hemolytic anemia.
Van Horn DK, Mortimer PP, Young N, Hanson GR.
Am J Pediatr Hematol Oncol. 1986;8(3):235-9.
Human parvovirus (HPV) infection has recently been implicated as the cause of aplastic crisis in patients with hemolytic anemias such as congenital spherocytosis and sickle cell anemia.
6414355
 MALE Adult
Clomiphene-responsive hypogonadism in sickle cell anemia.
Landefeld CS, Schambelan M, Kaplan SL, Embury SH.
Ann Intern Med. 1983;99(4):480-3.
Their sickle cell disease was characterized by infrequent crises, severe hemolytic anemia, urinary iron loss, and iron deficiency.