Sickle cell anemia

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Reticulocytopenia

A reduced number of reticulocytes in the peripheral blood.


Total: 2

                       


(per page)
PMID (PMCID)
26207780
 FEMALE
Unexpected Anemia and Reticulocytopenia in an Adolescent With Sickle Cell Anemia Receiving Chronic Transfusion Therapy.
Blauel ER, Grossmann LT, Vissa M, Miller ST.
J Pediatr Hematol Oncol. 2015;37(7):e438-40.
In a patient with sickle cell disease receiving chronic transfusion, exacerbation of anemia with reticulocytopenia must prompt consideration of a delayed hemolytic transfusion reaction with hyperhemolysis, as further transfusion may worsen this condition; definitive diagnosis is sometimes difficult.
26207780
 FEMALE
Unexpected Anemia and Reticulocytopenia in an Adolescent With Sickle Cell Anemia Receiving Chronic Transfusion Therapy.
Blauel ER, Grossmann LT, Vissa M, Miller ST.
J Pediatr Hematol Oncol. 2015;37(7):e438-40.
A 16-year-old with sickle cell disease receiving chronic transfusion of modified intensity (goal to maintain hemoglobin S<50%) who developed symptomatic anemia with reticulocytopenia was later shown to have had transient aplastic crisis.