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Sickle cell anemia

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Anemia

A reduction in erythrocytes volume or hemoglobin concentration.

Total: 35

(per page)

PMID (PMCID)
27479018	FEMALE
	Fulminant Liver Failure in a Child With beta-Thalassemia on Deferasirox: A Case Report.
	Ramaswami A, Rosen DJ, Chu J, Wistinghausen B, Arnon R. J Pediatr Hematol Oncol. 2017;39(3):235-237.
	Deferesirox (DFX), an oral chelating agent, is used to treat chronic iron overload in several hematological diseases such as 946-thalassemia, sickle cell disease, and myelodysplastic anemia.
27994488 (5153297)	OTHER
	An unfortunate case of acquired hemochromatosis: a case report review of the clinical presentation, diagnosis, management, and prognosis.
	Tariq A, Westra K, Santo A. Int Med Case Rep J. 2016;9:385-387.
	A 52-year-old African American woman with chronic anemia secondary to sickle cell anemia and history of multiple blood transfusions presented with elevated serum ferritin (8000 ng/mL) and bilirubin (16.8 mg/dL).
26171586	FEMALE	Child
	Extramedullary hematopoiesis of the liver in a child with sickle cell disease: A rare complication.
	Barrier A, Willy S, Slone JS. Pediatr Int. 2015;57(4):770-2.
	We present the case of a 7-year-old Cameroonian girl with sickle cell disease (SCD) who presented with progressive abdominal distension, fever, severe anemia, respiratory distress, and fatigue.
25976779	MIXED_SAMPLE	Adult
	Fanconi's Anemia Effect or Sickle Cell Anemia Effect: That is the Question.
	Unal S, Chui DH, Gumruk F. Hemoglobin. 2015;39(4):287-9.
	Fanconi's Anemia Effect or Sickle Cell Anemia Effect: That is the Question.
26327979 (4546797)	FEMALE	Adult
	Hashimoto's thyroiditis and acute chest syndrome revealing sickle cell anemia in a 32 years female patient.
	Igala M, Nsame D, Ova JD, Cherkaoui S, Oukkach B, Quessar A. Pan Afr Med J. 2015;21:142.
	We report the case of a 32 years old women admitted for chest pain and haemolysis anemia in which Hashimoto's thyroiditis and sickle cell anemia were found.
26207780	FEMALE
	Unexpected Anemia and Reticulocytopenia in an Adolescent With Sickle Cell Anemia Receiving Chronic Transfusion Therapy.
	Blauel ER, Grossmann LT, Vissa M, Miller ST. J Pediatr Hematol Oncol. 2015;37(7):e438-40.
	In a patient with sickle cell disease receiving chronic transfusion, exacerbation of anemia with reticulocytopenia must prompt consideration of a delayed hemolytic transfusion reaction with hyperhemolysis, as further transfusion may worsen this condition; definitive diagnosis is sometimes difficult.
26207780	FEMALE
	Unexpected Anemia and Reticulocytopenia in an Adolescent With Sickle Cell Anemia Receiving Chronic Transfusion Therapy.
	Blauel ER, Grossmann LT, Vissa M, Miller ST. J Pediatr Hematol Oncol. 2015;37(7):e438-40.
	A 16-year-old with sickle cell disease receiving chronic transfusion of modified intensity (goal to maintain hemoglobin S<50%) who developed symptomatic anemia with reticulocytopenia was later shown to have had transient aplastic crisis.
26207780	FEMALE
	Unexpected Anemia and Reticulocytopenia in an Adolescent With Sickle Cell Anemia Receiving Chronic Transfusion Therapy.
	Blauel ER, Grossmann LT, Vissa M, Miller ST. J Pediatr Hematol Oncol. 2015;37(7):e438-40.
	Unexpected Anemia and Reticulocytopenia in an Adolescent With Sickle Cell Anemia Receiving Chronic Transfusion Therapy.
26005936	MIXED_SAMPLE	Adult
	[What if it is not an acute pyelonephritis? A monocentric experience of renal infarcts].
	Radin E, Izzo C, Quaglia M, Merlotti G, Nappo A, Battista M, Guglielmetti G, Stratta P. G Ital Nefrol. 2015;32(2):.
	The labs showed a anemia due to a sickle cell disease (SLC).
25035790	OTHER
	A novel case report of sickle cell disease-associated immunoglobulin A nephropathy: the diagnostic value of erythrocyte dysmorphism evaluation.
	Silva GE, Teixeira AC, Vergna JG, Salgado-Filho N, Crivellentti LZ, Costa RS, Dantas M. Int J Clin Exp Med. 2014;7(6):1619-22.
	Sickle cell disease is a severe disease with a genetic pattern; it may cause anemia, vaso-occlusive phenomena, and multiorgan injury.
25053687	FEMALE	Adult
	Adrenal myelolipoma, cholelithiasis and calcified spleen: retrospective diagnosis of sickle cell anemia using a novel triad of abdominal imaging findings.
	Jakhere SG, Kumbhar RS, Dhongade HV. Acta Med Indones. 2014;46(2):134-7.
	Although in our case the patient was diagnosed to have sickle cell anemia depending on the abnormal morphology of red cells and hemoglobin electrophoresis, it should be remembered that this triad of findings may be seen in other hemoglobinopathies which induce a state of chronic anemia.
24257463	FEMALE	Infant
	Sickle cell disease and HIV: a case highlighting management challenges for children in a resource-limited setting.
	Odera EB, Kwobah C, Stone G, Some F, Vreeman RC. J Int Assoc Provid AIDS Care. 2014;13(2):113-6.
	Sickle cell disease results in chronic anemia and a variety of acute and chronic complications that can lead to early mortality.
23958767	FEMALE
	A young adult Jehovah's Witness with severe anemia.
	Ukachi N, Morrison W, Vanhorn S, Sundaram R, Lantos JD. Pediatrics. 2013;132(3):547-51.
	An 18-year-old Jehovah's Witness with sickle cell disease has life-threatening anemia.
23281181	MALE
	Massive splenic infarction in an adolescent with hemoglobin S-HPFH.
	Whyte D, Forget B, Chui DH, Luo HY, Pashankar F. Pediatr Blood Cancer. 2013;60(7):E49-51.
	These patients have no anemia, little evidence of hemolysis and generally have a benign clinical course compared to other types of sickle cell anemia.
23340961	FEMALE	Child
	Sickle cell disease with double stroke in a Moroccan family.
	Hamzi K, Itto AB, Jouhadi Z, Slassi I, Nadifi S. J Mol Neurosci. 2013;50(2):311-3.
	The sickle-cell disease is a group of chronic hemolytic diseases which associates three types of injuries: severe anemia, severe infections, and ischemic vaso-occlusive crisis that are secondary to conflicts between small vessels and red blood cells too deformable.
22371199	MALE	Adult
	Charcot-Marie-Tooth disease presenting as a nonhealing ulcer in a 26-year-old man.
	Judhan RJ, Maharaj SR, Perry A, Dellon AL, Maharaj D. Microsurgery. 2012;32(3):223-6.
	Neuropathic ulcers are usually associated with several well-known disorders including diabetes mellitus, tabes dorsalis, pernicious anemia, and sickle cell disease.
22885163	MIXED_SAMPLE	Adult
	Methemoglobinemia and ascorbate deficiency in hemoglobin E beta thalassemia: metabolic and clinical implications.
	Allen A, Fisher C, Premawardhena A, Bandara D, Perera A, Allen S, St Pierre T, Olivieri N, Weatherall D. Blood. 2012;120(15):2939-44.
	Because methemoglobin levels are modified by several mechanisms and may play a role in both adaptation to anemia and vascular damage, there is a strong case for its further study in other forms of thalassemia and sickle-cell anemia, particularly when splenic function is defective.
21655030 (3101768)	OTHER
	Anesthetic management of a patient with sickle beta thalassemia.
	Bharati S, Das S, Majee P, Mandal S. Saudi J Anaesth. 2011;5(1):98-100.
	Sickle cell disease is a congenital condition and its most common clinical manifestation is anemia due to chronic hemolysis.
21415949 (3033104)	OTHER
	Major artery occlusion: a rare complication of sickle cell disease.
	Agha A, Al-Hakami M, Shabbir G. Mediterr J Hematol Infect Dis. 2010;2(1):e2010007.
	Sickle cell disease is hereditary hemoglobinopathy which causes haemolytic anemia, vaso-occlusive crisis, ischemic injuries and many other morbidities like cerebral infarction.
19418550 (4360980)	MIXED_SAMPLE	Child
	Simultaneous acute splenic sequestration and transient aplastic crisis in children with sickle cell disease.
	Yates AM, Hankins JS, Mortier NA, Aygun B, Ware RE. Pediatr Blood Cancer. 2009;53(3):479-81.
	Acute splenic sequestration crisis (ASSC) is a hematological emergency in young children with sickle cell disease (SCD), characterized by worsening anemia and splenomegaly, usually with reticulocytosis and thrombocytopenia.