Sickle cell anemia

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Acidosis

Abnormal acid accumulation or depletion of base.


Total: 6

                       


(per page)
PMID (PMCID)
30574230
 FEMALE Middle Aged
Vanishing spleen syndrome post right partial nephrectomy in a sicklemic patient.
Khan K, Leroux O, Saeed S, Iqbal F, Ahmed L, Davis-Joseph B.
Pan Afr Med J. 2018;30:211.
The spleen is the most affected organ in sickle cell disease and the mechanism of auto infarction is thought to result from the crystallization of abnormal hemoglobin during periods of hypoxia or acidosis resulting in parenchymal ischemia and ultimately tissue necrosis.
27984409
 FEMALE Adult
Sickle Cell Disease, Severe Acidosis, and Inhalation Injury: Case Report of Neurologically Intact Survival After Cardiac Arrest From Smoke Inhalation.
Siddiqui Z, Ladha P, Dissanaike S.
J Burn Care Res. 2017;38(3):e686-e688.
We present the unusual case of complete neurologic survival after prolonged hypoxia, severe acidosis, out of hospital cardiac arrest, and exposure to high levels of carbon monoxide poisoning in a patient with sickle cell disease.
27984409
 FEMALE Adult
Sickle Cell Disease, Severe Acidosis, and Inhalation Injury: Case Report of Neurologically Intact Survival After Cardiac Arrest From Smoke Inhalation.
Siddiqui Z, Ladha P, Dissanaike S.
J Burn Care Res. 2017;38(3):e686-e688.
Sickle Cell Disease, Severe Acidosis, and Inhalation Injury: Case Report of Neurologically Intact Survival After Cardiac Arrest From Smoke Inhalation.
21461009
 MIXED_SAMPLE Child
[Co-inheritance of autosomal dominant polycystic kidney disease and sickle cell trait in African Americans].
Peces R, Peces C, Cuesta-Lopez E, Vega-Cabrera C, Azorin S, Perez-Duenas V, Selgas R.
Nefrologia. 2011;31(2):162-8.
Metabolic or environmental changes such as hypoxia, acidosis, dehydration, hyperosmolality or hyperthermia may transform silent sickle-cell trait into a syndrome resembling sickle-cell disease with vaso-occlusive crisis due to an accumulation of low deformable red blood cells in the microcirculation originating haematuria from papilar necrosis.
19999907
 MALE Middle Aged
The use of barbiturate coma as salvage therapy in a postoperative Jehovah's Witness patient with life-threatening anemia.
Wang SW, Badami CD, Deitch EA.
Am Surg. 2009;75(12):1175-8.
In this report, we present the case of a 52-year-old Jehovah's Witness with sickle cell disease in whom he and his family refused blood products for the treatment of severe anemia associated with profound and progressive acidosis, acute oliguric renal failure, and hemodynamic instability.
3826133
 MALE Adult
Priapism and dialysis.
Singhal PC, Lynn RI, Scharschmidt LA.
Am J Nephrol. 1986;6(5):358-61.
Additional considerations included dialysis-induced hypoxemia and acidosis which have been known to precipitate priapism in patients with sickle cell disease or trait.