Name: PubCaseFinder
License: http://creativecommons.org/licenses/by/2.1/jp/
Keywords: PubCaseFinder,PCF,Rare Disease,Phenotype,Gene,Match,Assist

Sickle cell anemia

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Hypersplenism

A malfunctioning of the spleen in which it prematurely destroys red blood cells.

Total: 1

(per page)

PMID (PMCID)
30499910	MALE	Child
	Massive Splenic Infarction in a Child With Sickle Cell Disease on Chronic Transfusion Therapy.
	Pereda MA, Isaac J, Zhang Y, Jayakumar R, Gupta R, Miller ST. J Pediatr Hematol Oncol. 2019;41(2):e79-e82.
	We report a case of MSI in a 12-year-old boy with homozygous sickle cell anemia (Hb SS) whose chronic transfusion therapy resulted in hypersplenism.