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Sickle cell anemia

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Constipation

Infrequent or difficult evacuation of feces.

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PMID (PMCID)
21642788	MALE
	Cholelithiasis in a toddler with sickle cell disease.
	Schinasi DA, Mistry RD, Mistry R. Pediatr Emerg Care. 2011;27(6):533-4.
	In addition to more common etiologies, such as gastroenteritis, constipation, and urinary tract infection, the differential diagnoses of acute abdominal pain in young children with sickle cell disease include vaso-occlusive pain crisis and splenic sequestration.