Sickle cell anemia

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Abdominal pain

An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) and perceived to originate in the abdomen.


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PMID (PMCID)
27348553
 MALE
An Hepatic Abscess in a Patient With Sickle Cell Anemia.
Marolf MD, Chaudhary M, Kaplan SL.
Pediatr Infect Dis J. 2016;35(11):1269-1270.
The diagnosis of hepatic abscess merits consideration in sickle cell disease patients presenting with fever without a source and/or abdominal pain.
27162524
(4853877)
 OTHER
PERCUTANEOUS LAPAROSCOPIC TROCAR DRAINAGE OF HEPATIC ABSCESS IN A SICKLE CELL DISEASE PATIENT - A CASE REPORT.
Afuwape OO, Chibuzo IN, Ayandipo OO, Nwafulume NA.
Ann Ib Postgrad Med. 2015;13(2):110-2.
A 25 year old Nigerian male with sickle cell disease presented with right sided upper abdominal pain, fever, massive hepatomegaly, neutrophilic leucocytosis and mildly deranged liver enzymes.
26613743
(4671447)
 MALE Adult
Rare but Lethal Hepatopathy-Sickle Cell Intrahepatic Cholestasis and Management Strategies.
Malik A, Merchant C, Rao M, Fiore RP.
Am J Case Rep. 2015;16:840-3.
We present the case of a 31-year-old man with past medical history of sickle cell disease and cholecystectomy who was admitted with uncomplicated vaso occlusive crisis and during the hospital stay developed fever, upper abdominal pain, and jaundice.
24247814
 FEMALE Child
Abdominal pain in children with sickle cell disease.
Rhodes MM, Bates DG, Andrews T, Adkins L, Thornton J, Denham JM.
J Clin Gastroenterol. 2014;48(2):99-105.
Abdominal pain in children with sickle cell disease.
23657515
 FEMALE Adult
Acute splenic sequestration in a pregnant woman with homozygous sickle-cell anemia.
Maia CB, Nomura RM, Igai AM, Fonseca GH, Gualandro SM, Zugaib M.
Sao Paulo Med J. 2013;131(2):123-6.
A 25-year-old woman with homozygous (SS) sickle-cell disease was hospitalized at 32 weeks' of gestation presenting weakness, abdominal pain, fever and hemoglobin of 2.4 g/dl.
20465425
 MALE Child
Cholecystitis and cholelithiasis associated with an intramural fasciitis-like proliferation and osseous metaplasia.
Rege TA, Vargas SO.
Pediatr Dev Pathol. 2011;14(1):80-3.
We report a 7-year-old boy with sickle cell disease who presented with right upper quadrant abdominal pain.
21642788
 MALE
Cholelithiasis in a toddler with sickle cell disease.
Schinasi DA, Mistry RD, Mistry R.
Pediatr Emerg Care. 2011;27(6):533-4.
In addition to more common etiologies, such as gastroenteritis, constipation, and urinary tract infection, the differential diagnoses of acute abdominal pain in young children with sickle cell disease include vaso-occlusive pain crisis and splenic sequestration.
21642788
 MALE
Cholelithiasis in a toddler with sickle cell disease.
Schinasi DA, Mistry RD, Mistry R.
Pediatr Emerg Care. 2011;27(6):533-4.
We describe a case of a toddler with sickle cell disease initially presenting with abdominal pain who was found to have symptomatic cholelithiasis.
22068059
 FEMALE
Gastric trichobezoar: abdominal mass in a child with sickle cell disease.
Sciarretta JD, Bond SJ.
Pediatr Emerg Care. 2011;27(11):1014-5.
Different from previously reported cases, we present a 3-year-old girl with sickle cell disease with complaints of acute abdominal pain, suspecting sickle cell splenic sequestration.
19634596
 FEMALE Adult
Sickle cell-induced ischemic colitis.
Stewart CL, Menard GE.
J Natl Med Assoc. 2009;101(7):726-8.
Our patient was a 29-year-old female with sickle cell disease who was admitted with left lower quadrant abdominal pain.
18176010
 MALE
Bacteroides (Parabacteroides) distasonis splenic abscess in a sickle cell patient.
Al-Tawfiq JA.
Intern Med. 2008;47(1):69-72.
Here we describe an 18 year-old boy with sickle cell disease and left upper quadrant abdominal pain.
18421713
 MALE
Biloma and pneumobilia in sickle cell disease.
Lebensburger J, Esbenshade A, Blakely M, Hankins J, Wang W.
Pediatr Blood Cancer. 2008;51(2):288-90.
Spontaneous biloma and pneumobilia developed in a patient with sickle cell disease (SCD) who presented with acute abdominal pain, jaundice, and fever.
18390028
 FEMALE Adult
Ischemic duodenal ulcer, an unusual presentation of sickle cell disease.
Julka RN, Aduli F, Lamps LW, Olden KW.
J Natl Med Assoc. 2008;100(3):339-41.
Abdominal pain, a common complaint in sickle cell disease, can be due to an uncommon etiology, ischemic duodenal ulceration.
17847767
 FEMALE Adult
Spontaneous uterine artery rupture during pregnancy in a woman with sickle cell disease: a case report.
Fiori O, Prugnolles H, Darai E, Uzan S, Berkane N.
J Reprod Med. 2007;52(7):657-8.
A 28-year-old, nulliparous woman with sickle cell disease was admitted at 27 weeks of gestation for sharp abdominal pain radiating to the right flank.
16215723
 FEMALE Child
Ischaemic cholangiopathy and sickle cell disease.
Ahmed M, Dick M, Mieli-Vergani G, Harrison P, Karani J, Dhawan A.
Eur J Pediatr. 2006;165(2):112-3.
We report a case of a 6-year-old girl of Afro-Caribbean origin, known to have sickle cell disease (SCD), with recurrent history of jaundice and abdominal pain.
12827657
 MIXED_SAMPLE Adult
Acute pancreatitis during sickle cell vaso-occlusive painful crisis.
Ahmed S, Siddiqui AK, Siddiqui RK, Kimpo M, Russo L, Mattana J.
Am J Hematol. 2003;73(3):190-3.
Acute pancreatitis is rarely included as a cause of abdominal pain in patients with sickle cell disease.
12827657
 MIXED_SAMPLE Adult
Acute pancreatitis during sickle cell vaso-occlusive painful crisis.
Ahmed S, Siddiqui AK, Siddiqui RK, Kimpo M, Russo L, Mattana J.
Am J Hematol. 2003;73(3):190-3.
Acute pancreatitis should be considered in the differential diagnosis of abdominal pain in patients with sickle cell disease.
12563093
 MALE
Myocardial infarction and transient ventricular dysfunction in an adolescent with sickle cell disease.
Deymann AJ, Goertz KK.
Pediatrics. 2003;111(2):E183-7.
We report a case of an adolescent who had sickle cell disease and previous evidence of myocardial damage and presented with abdominal pain and rapid progression to cardiogenic shock and subsequent development of myocardial infarction.
12883614
 FEMALE Adult
Pigment polyp in the common bile duct.
Meshikhes AW, Al-Talaq FT, Al-Faraj AA, Al-Moomen SA.
Saudi Med J. 2003;24(7):776-7.
We report here a case of a young female with sickle cell disease and a past history of open cholecystectomy 10 years ago presenting with intermittent upper abdominal pain and jaundice.
12394969
 MALE Adult
Sickle cell disease, extreme hyperbilirubinemia, and pericardial tamponade: case report and review of the literature.
Khurshid I, Anderson L, Downie GH, Pape GS.
Crit Care Med. 2002;30(10):2363-7.
Sickle cell intrahepatic cholestasis, a potentially fatal complication of sickle cell disease, can present with abdominal pain, acute hepatomegaly, coagulopathy, hyperbilirubinemia, and fulminant hepatic failure.