Sickle cell anemia

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Apnea

Lack of breathing with no movement of the respiratory muscles and no exchange of air in the lungs. This term refers to a disposition to have recurrent episodes of apnea rather than to a single event.


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(per page)
PMID (PMCID)
3408243
 FEMALE Child
Stroke associated with obstructive sleep apnea in a child with sickle cell anemia.
Robertson PL, Aldrich MS, Hanash SM, Goldstein GW.
Ann Neurol. 1988;23(6):614-6.
Moreover, because stroke in patients with sickle cell anemia, and maximal tonsillar enlargement (the most common cause of obstructive apnea in children) both have peak incidence at the same age (6-7 years), obstructive sleep apnea may be an important factor in the development of stroke in other children with sickle cell anemia.
3408243
 FEMALE Child
Stroke associated with obstructive sleep apnea in a child with sickle cell anemia.
Robertson PL, Aldrich MS, Hanash SM, Goldstein GW.
Ann Neurol. 1988;23(6):614-6.
Moreover, because stroke in patients with sickle cell anemia, and maximal tonsillar enlargement (the most common cause of obstructive apnea in children) both have peak incidence at the same age (6-7 years), obstructive sleep apnea may be an important factor in the development of stroke in other children with sickle cell anemia.